3D printing: an emerging tool for novel microfluidics and lab-on-a-chip applications
In the past few years, 3D printing technology has witnessed an explosive growth,
penetrating various aspects of our lives. Current best-in-class 3D printers can fabricate …
penetrating various aspects of our lives. Current best-in-class 3D printers can fabricate …
Particle squeezing in narrow confinements
Many lab-on-a-chip applications require processing of droplets, cells, and particles using
narrow confinements. The physics governing the process of a particle squeezing through …
narrow confinements. The physics governing the process of a particle squeezing through …
Oil–wall interaction induced droplet deformation dynamics in a capillary tube
Displacement of residual oil droplet in high water-cut oilfields can be optimized through the
understanding of droplet deformation dynamics. The current studies demonstrated that the …
understanding of droplet deformation dynamics. The current studies demonstrated that the …
Image-based spatio-temporal model of drug delivery in a heterogeneous vasculature of a solid tumor—Computational approach
The solute transport distribution in a tumor is an important criterion in the evaluation of the
cancer treatment efficacy. The fraction of killed cells after each treatment can quantify the …
cancer treatment efficacy. The fraction of killed cells after each treatment can quantify the …
Recent advances in microfluidic methods in cancer liquid biopsy
Early cancer detection, its monitoring, and therapeutical prediction are highly valuable,
though extremely challenging targets in oncology. Significant progress has been made …
though extremely challenging targets in oncology. Significant progress has been made …
Probing cell deformability via acoustically actuated bubbles
An acoustically actuated, bubble‐based technique is developed to investigate the
deformability of cells suspended in microfluidic devices. A microsized bubble is generated …
deformability of cells suspended in microfluidic devices. A microsized bubble is generated …
On the transport of particles/cells in high-throughput deterministic lateral displacement devices: Implications for circulating tumor cell separation
Deterministic lateral displacement (DLD), which takes advantage of the asymmetric
bifurcation of laminar flow around the embedded microposts, has shown promising …
bifurcation of laminar flow around the embedded microposts, has shown promising …
A data-driven approach to modeling cancer cell mechanics during microcirculatory transport
In order to understand the effect of cellular level features on the transport of circulating
cancer cells in the microcirculation, there has been an increasing reliance on high …
cancer cells in the microcirculation, there has been an increasing reliance on high …
A triplet parallelizing spiral microfluidic chip for continuous separation of tumor cells
H Chen - Scientific Reports, 2018 - nature.com
Inertial and deformability-based particles separations gradually attract more significant
attentions. In this work, we present a hybrid chip by combining the advantages of inertial and …
attentions. In this work, we present a hybrid chip by combining the advantages of inertial and …
Deformability-based circulating tumor cell separation with conical-shaped microfilters: Concept, optimization, and design criteria
Circulating tumor cells (CTCs) separation technology has made positive impacts on cancer
science in many aspects. The ability of detecting and separating CTCs can play a key role in …
science in many aspects. The ability of detecting and separating CTCs can play a key role in …