[HTML][HTML] The evolving landscape of antibody-drug conjugates in gynecologic cancers
A Tolcher, E Hamilton, RL Coleman - Cancer treatment reviews, 2023 - Elsevier
Despite significant advances in the treatment of cervical, ovarian, and uterine cancers with
the approvals of checkpoint and PARP inhibitors into standard treatment, patients with …
the approvals of checkpoint and PARP inhibitors into standard treatment, patients with …
Management of patients diagnosed with endometrial cancer: Comparison of guidelines
S Restaino, C Paglietti, M Arcieri, A Biasioli… - Cancers, 2023 - mdpi.com
Simple Summary Endometrial cancer has a high epidemiological impact, and its
management is part of everyday clinical practice. International guidelines have been …
management is part of everyday clinical practice. International guidelines have been …
Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry
L Vermij, JJ Jobsen, A León-Castillo… - British journal of …, 2023 - nature.com
Background Risk-assessment of endometrial cancer (EC) is based on clinicopathological
factors and molecular subgroup. It is unclear whether adding hormone receptor expression …
factors and molecular subgroup. It is unclear whether adding hormone receptor expression …
Durvalumab plus carboplatin/paclitaxel followed by maintenance durvalumab with or without olaparib as first-line treatment for advanced endometrial cancer: the …
PURPOSE Immunotherapy and chemotherapy combinations have shown activity in
endometrial cancer, with greater benefit in mismatch repair (MMR)–deficient (dMMR) than …
endometrial cancer, with greater benefit in mismatch repair (MMR)–deficient (dMMR) than …
Molecular classification predicts response to radiotherapy in the randomized PORTEC-1 and PORTEC-2 trials for early-stage endometrioid endometrial cancer
N Horeweg, RA Nout, IM Jürgenliemk-Schulz… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE The molecular classification of endometrial cancer (EC) has proven to have
prognostic value and is predictive of response to adjuvant chemotherapy. Here, we …
prognostic value and is predictive of response to adjuvant chemotherapy. Here, we …
Prediction of recurrence risk in endometrial cancer with multimodal deep learning
S Volinsky-Fremond, N Horeweg, S Andani… - Nature Medicine, 2024 - nature.com
Predicting distant recurrence of endometrial cancer (EC) is crucial for personalized adjuvant
treatment. The current gold standard of combined pathological and molecular profiling is …
treatment. The current gold standard of combined pathological and molecular profiling is …
[HTML][HTML] Verification of the prognostic precision of the new 2023 FIGO staging system in endometrial cancer patients–An international pooled analysis of three ESGO …
R Schwameis, F Fanfani, C Ebner… - European Journal of …, 2023 - Elsevier
Abstract Background Recently, the new 2023 International Federation of Gynecology and
Obstetrics (FIGO) staging system for endometrial cancer (EC) critically integrating new …
Obstetrics (FIGO) staging system for endometrial cancer (EC) critically integrating new …
Clinical behavior and molecular landscape of stage I P53-abnormal low-grade Endometrioid endometrial Carcinomas
A Jamieson, L Vermij, CJH Kramer, JJ Jobsen… - Clinical Cancer …, 2023 - AACR
Purpose: The clinical significance of the p53-abnormal (p53abn) molecular subtype in stage
I low-grade endometrioid endometrial carcinoma (EEC) is debated. We aimed to review …
I low-grade endometrioid endometrial carcinoma (EEC) is debated. We aimed to review …
Artificial intelligence-based risk stratification, accurate diagnosis and treatment prediction in gynecologic oncology
Y Jiang, C Wang, S Zhou - Seminars in cancer biology, 2023 - Elsevier
As data-driven science, artificial intelligence (AI) has paved a promising path toward an
evolving health system teeming with thrilling opportunities for precision oncology …
evolving health system teeming with thrilling opportunities for precision oncology …
[HTML][HTML] Endometrial cancer: molecular classification and future treatments
B Corr, C Cosgrove, D Spinosa, S Guntupalli - BMJ medicine, 2022 - ncbi.nlm.nih.gov
The treatment for endometrial cancer is rapidly evolving with the development of molecular
analysis and novel strategies. Surgical resection, cytotoxic chemotherapy, endocrine or …
analysis and novel strategies. Surgical resection, cytotoxic chemotherapy, endocrine or …