Cabotegravir/Rilpivirine: the last FDA-approved drug to treat HIV

E Taki, F Soleimani, A Asadi… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction The development of long-acting (LA) drugs has changed the management of
common medical conditions for human replication immunodeficiency virus (HIV). Cabenuva …

A systematic review and meta-analysis of tuberculous preventative therapy adverse events

L Melnychuk, S Perlman-Arrow… - Clinical Infectious …, 2023 - academic.oup.com
Background Tuberculosis preventative therapy (TPT) is a key part of the World Health
Organization's (WHO) end tuberculosis (TB) strategy. However, the occurrence of potentially …

Noncommunicable diseases burden and risk factors in a cohort of HIV+ elderly patients in Malawi

F Ciccacci, VT Tolno, AM Doro Altan… - AIDS Research and …, 2019 - liebertpub.com
HIV-infected patients have increased risk of noncommunicable diseases (NCDs). HIV+
patients in Africa are experiencing growing comorbidities due to increase in life expectancy …

Druggability modification strategies of the diarylpyrimidine‐type non‐nucleoside reverse transcriptase inhibitors

L Ding, C Zhuang, F Chen - Medicinal Research Reviews, 2021 - Wiley Online Library
Drug discovery of human immunodeficiency virus (HIV) is a hot field in medicinal chemistry
community for many years. The diarylpyrimidines (DAPYs) are the second‐generation non …

A matched cohort study investigating premature, accentuated, and accelerated aging in people living with HIV

TE Gooden, J Wang, DT Zemedikun, S Taylor… - HIV …, 2023 - Wiley Online Library
Introduction The impact of HIV infection on the aging process is disputed and largely
unknown. We aimed to identify whether people living with HIV experience premature …

Insertion of an amphipathic linker in a tetrapodal tryptophan derivative leads to a novel and highly potent entry inhibitor of enterovirus A71 clinical isolates

O Martí-Marí, R Abdelnabi, D Schols, J Neyts… - International Journal of …, 2023 - mdpi.com
AL-471, the leading exponent of a class of potent HIV and enterovirus A71 (EV-A71) entry
inhibitors discovered in our research group, contains four l-tryptophan (Trp) units bearing an …

Impact of lopinavir/ritonavir and efavirenz-based antiretroviral therapy on the lipid profile of Chinese HIV/AIDS treatment-naïve patients in Beijing: A retrospective study

L Dai, A Liu, H Zhang, H Wu, T Zhang, B Su… - Current HIV …, 2019 - ingentaconnect.com
Background: Antiretroviral therapy (ART) is associated with lipid abnormalities that
contribute to increased risk of cardiovascular (CV) events among patients with human …

[HTML][HTML] Conformational flexibility of the conserved hydrophobic pocket of HIV-1 gp41. Implications for the discovery of small-molecule fusion inhibitors

M Cano-Muñoz, S Jurado, B Morel… - International Journal of …, 2021 - Elsevier
During HIV-1 infection, the envelope glycoprotein subunit gp41 folds into a six-helix bundle
structure (6HB) formed by the interaction between its N-terminal (NHR) and C-terminal …

A systematic review assessing the association of inflammatory markers with kidney dysfunction in people living with HIV on highly active antiretroviral therapy

J Choshi, S Hanser, SE Mabhida, H Mokoena… - BMC Infectious …, 2024 - Springer
Monitoring chronic diseases, particularly kidney disorders, in people living with HIV (PLWH)
is of paramount importance. Here, a systematic search was conducted across electronic …

艾滋病病毒感染者启动高效抗逆转录病毒疗法对贫血发病的影响

郎晶晶, 陈盼盼, 朱黎丹, 辛辛, 许秋利, 刘乾乾, 汤琰… - 上海预防医学, 2023 - sjpm.org.cn
艾滋病病毒感染者启动高效抗逆转录病毒疗法对贫血发病的影响 中华预防医学会系列杂志 星期
首页 期刊介绍 1.杂志简介 2.编委会 3.发展历程 4.编辑部 在线期刊 1.当期目录 2.过刊浏览 3.优先 …