[HTML][HTML] Cell fate decisions, transcription factors and signaling during early retinal development
R Diacou, P Nandigrami, A Fiser, W Liu… - Progress in retinal and …, 2022 - Elsevier
The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …
How the extracellular matrix shapes neural development
KR Long, WB Huttner - Royal Society Open Biology, 2019 - royalsocietypublishing.org
During development, both cells and tissues must acquire the correct shape to allow their
proper function. This is especially relevant in the nervous system, where the shape of …
proper function. This is especially relevant in the nervous system, where the shape of …
Human neural tube morphogenesis in vitro by geometric constraints
Understanding human organ formation is a scientific challenge with far-reaching medical
implications,. Three-dimensional stem-cell cultures have provided insights into human cell …
implications,. Three-dimensional stem-cell cultures have provided insights into human cell …
Self-organizing models of human trunk organogenesis recapitulate spinal cord and spine co-morphogenesis
S Gribaudo, R Robert, B van Sambeek, C Mirdass… - Nature …, 2023 - nature.com
Integrated in vitro models of human organogenesis are needed to elucidate the multi-
systemic events underlying development and disease. Here we report the generation of …
systemic events underlying development and disease. Here we report the generation of …
Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites
INTRODUCTION Vertebrate development comprises multiple complex morphogenetic
processes that shape the embryonic body plan through self-organization of pluripotent stem …
processes that shape the embryonic body plan through self-organization of pluripotent stem …
[HTML][HTML] The single-cell and spatial transcriptional landscape of human gastrulation and early brain development
B Zeng, Z Liu, Y Lu, S Zhong, S Qin, L Huang, Y Zeng… - Cell Stem Cell, 2023 - cell.com
The emergence of the three germ layers and the lineage-specific precursor cells
orchestrating organogenesis represent fundamental milestones during early embryonic …
orchestrating organogenesis represent fundamental milestones during early embryonic …
Tissue mechanics in stem cell fate, development, and cancer
Cells in tissues experience a plethora of forces that regulate their fate and modulate
development and homeostasis. Cells sense mechanical cues through localized …
development and homeostasis. Cells sense mechanical cues through localized …
Imaging cellular forces with photonic crystals
Current techniques for visualizing and quantifying cellular forces have limitations in live cell
imaging, throughput, and multi-scale analysis, which impede progress in cell force research …
imaging, throughput, and multi-scale analysis, which impede progress in cell force research …
Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture
J Zhai, Y Xu, H Wan, R Yan, J Guo, R Skory, L Yan… - Cell, 2023 - cell.com
Neural tube (NT) defects arise from abnormal neurulation and result in the most common
birth defects worldwide. Yet, mechanisms of primate neurulation remain largely unknown …
birth defects worldwide. Yet, mechanisms of primate neurulation remain largely unknown …
Intrinsic mechanical cues and their impact on stem cells and embryogenesis
J Petzold, E Gentleman - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Although understanding how soluble cues direct cellular processes revolutionised the study
of cell biology in the second half of the 20th century, over the last two decades, new insights …
of cell biology in the second half of the 20th century, over the last two decades, new insights …