Tuberculosis remains a global health problem with an enormous burden of disease,
estimated at 10.4 million new cases in 2015. To stop the tuberculosis epidemic, it is critical …

Executive summary Tuberculosis can be treated, prevented, and cured. Rapid, sustained
declines in tuberculosis deaths in many countries during the past 50 years provide …

The coronavirus disease 2019 (COVID-19) pandemic is likely to be the defining global
health crisis of our generation. As the United Nations Development Programme highlighted …

Background Case fatality ratios in children with tuberculosis are poorly understood—
particularly those among children with HIV and children not receiving tuberculosis treatment …

The annual risk of infection with Mycobacterium tuberculosis determines a population's
exposure level and thus the fraction of incident tuberculosis resulting from recent infection …

Despite the high coverage of directly observed treatment short-course (DOTS), tuberculosis
(TB) continues to affect 10.4 million people each year, and kills 1.8 million. High TB mortality …

To halt the global tuberculosis epidemic, transmission must be stopped to prevent new
infections and new cases. Identification of individuals with tuberculosis and prompt initiation …

Around one third of the world's population may harbour latent tuberculosis infection (LTBI),
an asymptomatic immunological state that confers a heightened risk of subsequently …

Given the dual epidemics of HIV and tuberculosis in sub-Saharan Africa and evidence
suggesting a disproportionate burden of these diseases among detainees in the region, we …

The successful care of children and adolescents with TB requires a recognition of the risk
factors and clinical and radiographic signs of TB, especially when microbiologic testing is …