Biomarkers in the Diagnosis of Endometrial Precancers. Molecular Characteristics, Candidate Immunohistochemical Markers, and Promising Results of Three-Marker …

S Niu, K Molberg, DH Castrillon, E Lucas, H Chen - Cancers, 2024 - mdpi.com
Simple Summary Endometrial carcinoma is a common type of cancer in women, ranking as
the most frequent gynecological cancer and the fourth most common overall. Its occurrence …

β-Catenin, PAX2 and PTEN panel in the diagnosis of endometrial precancers: A case-based review

E Lucas, H Chen, SS Sahoo, K Carrick… - Diagnostic …, 2023 - Elsevier
Detection and management of endometrial precancers remain ongoing challenges in the
fields of pathology and gynecology, with implications for the need to decrease mortality from …

Utility of a Pax2, PTEN, and Β-Catenin panel in the diagnosis of atypical hyperplasia/Endometrioid intraepithelial Neoplasia in endometrial polyps

E Lucas, S Niu, M Aguilar, K Molberg… - The American Journal …, 2023 - journals.lww.com
The diagnosis of atypical hyperplasia/endometrioid intraepithelial neoplasm (AH/EIN) within
endometrial polyps (EMPs) often poses a diagnostic conundrum. Our previous studies …

Predicting Progestin Therapy Response With PTEN, PAX2, and β-Catenin in Patients With Endometrioid Precancer

N Liu, W Lin, Y Wang, Z Yao… - International Journal …, 2024 - journals.lww.com
This study investigates the predictive value of biomarkers PTEN, PAX2, and β-catenin for
therapeutic outcomes in patients with atypical endometrial hyperplasia or endometrioid …

Lesions sub‐diagnostic of endometrioid intra‐epithelial neoplasia/atypical hyperplasia: value of morphology and immunohistochemistry in predicting neoplastic …

N Wyvekens, GL Mutter, MR Nucci, DL Kolin… - …, 2024 - Wiley Online Library
Aims Areas of gland crowding that do not fulfil diagnostic criteria of endometrioid intra‐
epithelial neoplasia (EIN) are often encountered in endometrial biopsies. In this study, we …

β-catenin, PAX2, and PTEN Aberrancy Across the Spectrum of Endometrioid Ovarian Lesions

MM Del Mundo, M Aguilar, H Chen, S Niu… - International Journal …, 2024 - journals.lww.com
Endometriosis is a common condition, with the ovary being the most common anatomic site.
Endometriosis—particularly in the ovary—is associated with a risk of malignant progression …

[HTML][HTML] Utility of immunocytochemistry in diagnosing abdominopelvic washings from patients undergoing radical surgery for endometrial cancer

Z Lan, J Zhang, F Yang, X Ma, R He - CytoJournal, 2024 - ncbi.nlm.nih.gov
Objective: This study aimed to explore the efficacy of immunocytochemistry in diagnosing
abdominopelvic washings (APWs) and evaluate the superiority of cytology combined with …

Development and Maldevelopment of the Female Reproductive Tract

DH Castrillon - Gynecologic and Obstetric Pathology, 2024 - Springer
The female reproductive tract has its embryological origins in the paired Müllerian ducts and
their fusion to each other and the urogenital sinus. The Müllerian ducts give rise to the …