Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …

Tuberculosis (TB) remains one of the most widespread and leading deadliest diseases,
threats one-third of the world's population. Although numerous efforts have been undertaken …

One-third of the world's population infected tuberculosis (TB), and more than 1 million
deaths annually. The co-infection between the mainly pathogen Mycobacterium tuberculosis …

Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …

Hybridization, a strategy based on the covalent fusion of two or more existing
pharmacophores to create a single molecule with multiple mechanisms of action, represents …

In the search for new anti-mycobacterial agents, we revealed the importance of imidazo-[2, 1-
b]-thiazole and benzo-[d]-imidazo-[2, 1-b]-thiazole carboxamide derivatives. We designed, in …

Despite decades of dedicated research, there remains a dire need for new drugs against
tuberculosis (TB). Current therapies are generations old and problematic. Resistance to …

Tuberculosis (TB), a chronic infectious disease, is one of the greatest risks to human beings
and 10 million people were diagnosed with TB and 1.6 million died from this disease in …

Tuberculosis (TB), one of the most prevalent infections, is on the rise today. Although there
are drugs available in the market to combat this lethal disorder, there are several …