[HTML][HTML] Synthesis and pharmacological activities of pyrazole derivatives: A review
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
Triazole derivatives and their anti-tubercular activity
S Zhang, Z Xu, C Gao, QC Ren, L Chang, ZS Lv… - European journal of …, 2017 - Elsevier
Tuberculosis (TB) remains one of the most widespread and leading deadliest diseases,
threats one-third of the world's population. Although numerous efforts have been undertaken …
threats one-third of the world's population. Although numerous efforts have been undertaken …
Recent advances of pyrazole-containing derivatives as anti-tubercular agents
Z Xu, C Gao, QC Ren, XF Song, LS Feng… - European journal of …, 2017 - Elsevier
One-third of the world's population infected tuberculosis (TB), and more than 1 million
deaths annually. The co-infection between the mainly pathogen Mycobacterium tuberculosis …
deaths annually. The co-infection between the mainly pathogen Mycobacterium tuberculosis …
Emerging impact of triazoles as anti-tubercular agent
A Sharma, AK Agrahari, S Rajkhowa… - European Journal of …, 2022 - Elsevier
Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …
Recent advancements and developments in search of anti-tuberculosis agents: a quinquennial update and future directions
Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …
Quinolone–triazole hybrids and their biological activities
JH Xu, YL Fan, J Zhou - Journal of heterocyclic chemistry, 2018 - Wiley Online Library
Hybridization, a strategy based on the covalent fusion of two or more existing
pharmacophores to create a single molecule with multiple mechanisms of action, represents …
pharmacophores to create a single molecule with multiple mechanisms of action, represents …
[HTML][HTML] Design, synthesis and biological evaluation of benzo-[d]-imidazo-[2, 1-b]-thiazole and imidazo-[2, 1-b]-thiazole carboxamide triazole derivatives as …
S Chitti, K Van Calster, D Cappoen, A Nandikolla… - RSC …, 2022 - pubs.rsc.org
In the search for new anti-mycobacterial agents, we revealed the importance of imidazo-[2, 1-
b]-thiazole and benzo-[d]-imidazo-[2, 1-b]-thiazole carboxamide derivatives. We designed, in …
b]-thiazole and benzo-[d]-imidazo-[2, 1-b]-thiazole carboxamide derivatives. We designed, in …
[HTML][HTML] Vitamin in the crosshairs: targeting pantothenate and coenzyme a biosynthesis for new antituberculosis agents
HS Butman, TJ Kotzé, CS Dowd… - Frontiers in Cellular and …, 2020 - frontiersin.org
Despite decades of dedicated research, there remains a dire need for new drugs against
tuberculosis (TB). Current therapies are generations old and problematic. Resistance to …
tuberculosis (TB). Current therapies are generations old and problematic. Resistance to …
Opportunities and challenges of using five‐membered ring compounds as promising antitubercular agents
M Yan, L Xu, Y Wang, J Wan, T Liu… - Drug Development …, 2020 - Wiley Online Library
Tuberculosis (TB), a chronic infectious disease, is one of the greatest risks to human beings
and 10 million people were diagnosed with TB and 1.6 million died from this disease in …
and 10 million people were diagnosed with TB and 1.6 million died from this disease in …
[HTML][HTML] Inhibitors of pantothenate synthetase of Mycobacterium tuberculosis–a medicinal chemist perspective
Tuberculosis (TB), one of the most prevalent infections, is on the rise today. Although there
are drugs available in the market to combat this lethal disorder, there are several …
are drugs available in the market to combat this lethal disorder, there are several …