Simple Summary The transcription factor p53 is a crucial tumor suppressor that regulates
diverse cellular responses to protect against cancer development. Deactivating p53 …

The high mobility group A1 (HMGA1) gene plays an important role in numerous malignant
cancers. HMGA1 is an oncofoetal gene, and we have a certain understanding of the …

Breast cancer cells evade cell death by overexpressing SLC7A11, which functions by
transporting cystine into cells in exchange for intracellular glutamate facilitating glutathione …

This study investigates the role of circular RNA (circRNA) hsa_circ_0000515 in cervical
cancer and the underlying mechanism associated with microRNA-326 (miR-326) …

The inter-differentiation between cell states promotes cancer cell survival under stress and
fosters non-genetic heterogeneity (NGH). NGH is, therefore, a surrogate of tumor resilience …

Emerging evidence has revealed that miRNAs could upregulate the expression levels of
target genes. However, the molecular mechanism underlying upregulation of targets …

Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans
and it can be locally invasive and metastatic to distant sites. MicroRNAs (miRNAs or miRs) …

Tripeptide GSH is associated not only with the control and maintenance of redox cell
homeostasis, but also with the processes of detoxification, proliferation, cell differentiation …

Background Glioma is one of the most common and aggressive malignant tumors in central
nervous system. Recently, long non-coding RNA (lncRNA) HOXA11-AS has been reported …

HMGA1 and HMGA2 are chromatin architectural proteins that do not have transcriptional
activity per se, but are able to modify chromatin structure by interacting with the …