The heparins, well-known for their anticoagulant properties, may also have anti-
inflammatory effects that could contribute to their effectiveness in the treatment of venous …

Neutrophils have long been known as innate immune cells that phagocytose and kill
pathogens and mount inflammatory responses protecting the host from infection. In the past …

The majority of patients with cancer undergo at least one surgical procedure as part of their
treatment. Severe postsurgical infection is associated with adverse oncologic outcomes; …

Many aspects of neutrophil hyperactivity and its role in numerous immune responses still
remain a mystery. A new neutrophil mechanism was discovered recently, ie, the formation of …

Neutrophils constitute a critical part of innate immunity and are well known for their ability to
phagocytose and kill invading microorganisms. The microbicidal processes employed by …

Breast cancer is a leading cause of cancer death in women, worldwide. Fortunately, breast
cancer is relatively chemosensitive, with recent advances leading to the development of …

Venous thromboembolism is a frequent complication occurring in patients suffering from
neoplastic diseases. Since neutrophil extracellular traps (NETs) play an important role both …

Taking into account the previously reported relationship between inflammation and
carcinogenesis, and the scant amount of data concerning the role of neutrophil extracellular …

Ixolaris is a potent tick salivary anticoagulant that binds coagulation factor Xa (FXa) and
zymogen FX, with formation of a quaternary tissue factor (TF)/FVIIa/FX (a)/Ixolaris inhibitory …

The introduction of immunomodulatory drugs (IMiDs) has improved clinical outcome in
patients with multiple myeloma (MM). However, their use has been associated with a higher …