Mechanisms of deep brain stimulation
TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
Insights into the mechanisms of deep brain stimulation
K Ashkan, P Rogers, H Bergman… - Nature Reviews …, 2017 - nature.com
Despite long-term and widespread use of deep brain stimulation (DBS) in a variety of
neurological conditions, the underlying mechanisms of action have been elusive. Growing …
neurological conditions, the underlying mechanisms of action have been elusive. Growing …
[HTML][HTML] Probing and regulating dysfunctional circuits using deep brain stimulation
Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …
Deep brain stimulation
JS Perlmutter, JW Mink - Annu. Rev. Neurosci., 2006 - annualreviews.org
Deep brain stimulation (DBS) has provided remarkable benefits for people with a variety of
neurologic conditions. Stimulation of the ventral intermediate nucleus of the thalamus can …
neurologic conditions. Stimulation of the ventral intermediate nucleus of the thalamus can …
Translational principles of deep brain stimulation
Deep brain stimulation (DBS) has shown remarkable therapeutic benefits for patients with
otherwise treatment-resistant movement and affective disorders. This technique is not only …
otherwise treatment-resistant movement and affective disorders. This technique is not only …
An update on best practice of deep brain stimulation in Parkinson's disease
CJ Hartmann, S Fliegen, SJ Groiss… - Therapeutic …, 2019 - journals.sagepub.com
During the last 30 years, deep brain stimulation (DBS) has evolved into the clinical standard
of care as a highly effective treatment for advanced Parkinson's disease. Careful patient …
of care as a highly effective treatment for advanced Parkinson's disease. Careful patient …
Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson's disease
Gait disturbances and akinesia are extremely disabling in advanced Parkinson's disease. It
has been suggested that modulation of the activity of the pedunculopontine nucleus (PPN) …
has been suggested that modulation of the activity of the pedunculopontine nucleus (PPN) …
Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain
MP Kelly - Cellular signalling, 2018 - Elsevier
Deficits in brain function that are associated with aging and age-related diseases benefit
very little from currently available therapies, suggesting a better understanding of the …
very little from currently available therapies, suggesting a better understanding of the …
Deep brain stimulation mechanisms: the control of network activity via neurochemistry modulation
CC McIntyre, RW Anderson - Journal of Neurochemistry, 2016 - Wiley Online Library
Deep brain stimulation (DBS) has revolutionized the clinical care of late‐stage Parkinson's
disease and shows promise for improving the treatment of intractable neuropsychiatric …
disease and shows promise for improving the treatment of intractable neuropsychiatric …
Mechanisms of action of deep brain stimulation (DBS)
EB Montgomery Jr, JT Gale - Neuroscience & Biobehavioral Reviews, 2008 - Elsevier
Deep brain stimulation (DBS) is remarkably effective for a range of neurological and
psychiatric disorders that have failed pharmacological and cell transplant therapies. Clinical …
psychiatric disorders that have failed pharmacological and cell transplant therapies. Clinical …