Applications of ruthenium complex in tumor diagnosis and therapy
K Lin, ZZ Zhao, HB Bo, XJ Hao, JQ Wang - Frontiers in Pharmacology, 2018 - frontiersin.org
Ruthenium complexes are a new generation of metal antitumor drugs that are currently of
great interest in multidisciplinary research. In this review article, we introduce the …
great interest in multidisciplinary research. In this review article, we introduce the …
An overview of the potential medicinal and pharmaceutical properties of Ru (II)/(III) complexes
A Skoczynska, A Lewinski, M Pokora, P Paneth… - International Journal of …, 2023 - mdpi.com
This review examines the existing knowledge about Ru (II)/(III) ion complexes with a
potential application in medicine or pharmacy, which may offer greater potential in cancer …
potential application in medicine or pharmacy, which may offer greater potential in cancer …
New ruthenium-xanthoxylin complex eliminates colorectal cancer stem cells by targeting the heat shock protein 90 chaperone
LS Santos, VR Silva, MVL de Castro, RB Dias… - Cell Death & …, 2023 - nature.com
In this work, we describe a novel ruthenium-xanthoxylin complex,[Ru (phen) 2
(xant)](PF6)(RXC), that can eliminate colorectal cancer (CRC) stem cells by targeting the …
(xant)](PF6)(RXC), that can eliminate colorectal cancer (CRC) stem cells by targeting the …
Molecular design, spectroscopic, DFT, pharmacological, and molecular docking studies of novel ruthenium (III)–Schiff base complex: An inhibitor of progression in …
AFH Noureldeen, SW Aziz, SA Shouman… - International journal of …, 2022 - mdpi.com
A novel ruthenium (III)–pyrimidine Schiff base was synthesized and characterized using
different analytical and spectroscopic techniques. Molecular geometries of the ligand and …
different analytical and spectroscopic techniques. Molecular geometries of the ligand and …
A novel ruthenium complex with 5-fluorouracil suppresses colorectal cancer stem cells by inhibiting Akt/mTOR signaling
VR Silva, LS Santos, MVL de Castro, RB Dias… - Cell Death …, 2023 - nature.com
Abstract [Ru (5-FU)(PPh3) 2 (bipy)] PF6 (Ru/5-FU) is a novel ruthenium complex with 5-
fluorouracil with promising potential against colorectal cancer (CRC). In the present study …
fluorouracil with promising potential against colorectal cancer (CRC). In the present study …
Cytostatic and anti-tumor potential of Ajwa date pulp against human hepatocellular carcinoma HepG2 cells
Ajwa dates (Phoenix dactylifera L.) are used by traditional therapeutic practitioners for
several health benefits but most remain to be scientifically validated. In this study, we …
several health benefits but most remain to be scientifically validated. In this study, we …
Organoruthenium complexes with benzo-fused pyrithiones overcome platinum resistance in ovarian cancer cells
J Kladnik, JPC Coverdale, J Kljun, H Burmeister… - Cancers, 2021 - mdpi.com
Simple Summary Ovarian cancer is the fifth most common cancer in the developing world,
with many front-line treatments combining paclitaxel with platinum-based anticancer agents …
with many front-line treatments combining paclitaxel with platinum-based anticancer agents …
Novel lawsone-containing ruthenium (II) complexes: Synthesis, characterization and anticancer activity on 2D and 3D spheroid models of prostate cancer cells
RA De Grandis, PWS Dos Santos, KM de Oliveira… - Bioorganic …, 2019 - Elsevier
This study describes a series of newly synthesized phosphine/diimine ruthenium complexes
containing the lawsone as bioligand with enhanced cytotoxicity against different cancer …
containing the lawsone as bioligand with enhanced cytotoxicity against different cancer …
[HTML][HTML] A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK …
MS Oliveira, MIF Barbosa, TB de Souza, DRM Moreira… - Redox Biology, 2019 - Elsevier
Piplartine (piperlongumine) is a plant-derived compound found in some Piper species that
became a novel potential antineoplastic agent. In the present study, we synthesized a novel …
became a novel potential antineoplastic agent. In the present study, we synthesized a novel …
Two novel Pd thiosemicarbazone complexes as efficient and selective antitumoral drugs
Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in
2020. Palladium complexes can be used as anticancer and pharmacological agents as a …
2020. Palladium complexes can be used as anticancer and pharmacological agents as a …