The importance of 3D fibre architecture in cancer and implications for biomaterial model design
JC Ashworth, TR Cox - Nature Reviews Cancer, 2024 - nature.com
The need for improved prediction of clinical response is driving the development of cancer
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …
[HTML][HTML] Recent advancements in optical harmonic generation microscopy: Applications and perspectives
S JamesDarian, J CampagnolaPaul - BME frontiers, 2021 - spj.science.org
Second harmonic generation (SHG) and third harmonic generation (THG) microscopies
have emerged as powerful imaging modalities to examine structural properties of a wide …
have emerged as powerful imaging modalities to examine structural properties of a wide …
Collagen fiber orientation and dispersion in the upper cervix of non-pregnant and pregnant women
The structural integrity of the cervix in pregnancy is necessary for carrying a pregnancy until
term, and the organization of human cervical tissue collagen likely plays an important role in …
term, and the organization of human cervical tissue collagen likely plays an important role in …
Automated quantification of three-dimensional organization of fiber-like structures in biological tissues
Fiber-like structures are prevalent in biological tissues, yet quantitative approaches to
assess their three-dimensional (3D) organization are lacking. We develop 3D directional …
assess their three-dimensional (3D) organization are lacking. We develop 3D directional …
Label-free, multi-parametric assessments of cell metabolism and matrix remodeling within human and early-stage murine osteoarthritic articular cartilage
Z Liu, CK Hui Mingalone, E Gnanatheepam… - Communications …, 2023 - nature.com
Osteoarthritis (OA) is characterized by the progressive deterioration of articular cartilage,
involving complicated cell-matrix interactions. Systematic investigations of dynamic cellular …
involving complicated cell-matrix interactions. Systematic investigations of dynamic cellular …
Modeling controlled cortical impact injury in 3D brain‐like tissue cultures
V Liaudanskaya, JY Chung, C Mizzoni… - Advanced …, 2020 - Wiley Online Library
Traumatic brain injury (TBI) survivors suffer long term from mental illness,
neurodegeneration, and neuroinflammation. Studies of 3D tissue models have provided …
neurodegeneration, and neuroinflammation. Studies of 3D tissue models have provided …
Mapping port wine stain in vivo by optical coherence tomography angiography and multi-metric characterization
Port wine stain (PWS) is a congenital cutaneous capillary malformation composed of ecstatic
vessels, while the microstructure of these vessels remains largely unknown. Optical …
vessels, while the microstructure of these vessels remains largely unknown. Optical …
Mapping physiological and pathological functions of cortical vasculature through aggregation-induced emission nanoprobes assisted quantitative, in vivo NIR-II …
Cerebrovascular disease includes all disorders that affect cerebrovascular and cerebral
circulation. Unfortunately, there is currently a lack of a systematic method to image blood …
circulation. Unfortunately, there is currently a lack of a systematic method to image blood …
[PDF][PDF] 生物组织大深度定量光学成像
文志博， 刘开元， 蒋慎益， 何木斌， 韩涛， 斯科… - Acta Optica …, 2022 - researching.cn
摘要近年来, 面向生物组织大深度光学成像的方法不断发展, 其中包括光学相干层析,
多光子成像和自适应光学等. 介绍了浙江大学光电科学与工程学院近年来在生物组织大深度定量 …
多光子成像和自适应光学等. 介绍了浙江大学光电科学与工程学院近年来在生物组织大深度定量 …
Systemic sclerosis dermal fibroblasts induce cutaneous fibrosis through lysyl oxidase–like 4: new evidence from three‐dimensional skin‐like tissues
Objective Systemic sclerosis (SS c) is a clinically heterogeneous disease characterized by
increased collagen accumulation and skin stiffness. Our previous work has demonstrated …
increased collagen accumulation and skin stiffness. Our previous work has demonstrated …