Biomedical application of porphyrin-based amphiphiles and their self-assembled nanomaterials

J Han, Y Liu, D Peng, J Liu, D Wu - Bioconjugate Chemistry, 2023 - ACS Publications
Porphyrins have been vastly explored and applied in many cutting-edge fields with plenty of
encouraging achievements because of their excellent properties. As important derivatives of …

Progress of porphyrin-based nanoassemblies for cancer theranostics

M Wang, G Huang, Z You, R Jia, Y Zhong… - Chemical Research in …, 2023 - Springer
Porphyrins are indispensable in almost all forms of life. As photosensitizers, porphyrins have
excellent imaging, photodynamic, photothermal, chemotherapeutic, and enzymatic …

Self-assembled porphyrin–peptide cages for photodynamic therapy

C Ghosh, LMA Ali, Y Bessin, S Clément… - Organic & …, 2024 - pubs.rsc.org
The development of photodynamic therapy requires access to smart photosensitizers which
combine appropriate photophysical and biological properties. Interestingly, supramolecular …

Self-assembly strategies of organic small-molecule photosensitizers for photodynamic therapy

X Xiong, J Liu, L Wu, S Xiong, W Jiang… - Coordination Chemistry …, 2024 - Elsevier
In recent years, the use of organic small-molecule photosensitizers, which make up the
majority of photosensitizers, has significantly enhanced the therapeutic outcomes of various …

Direct Construction of Corrole‐Peptide Conjugates by Controllable Bilane Formation on Resin

Y Wu, HF Chau, HY Kai, WS Tam… - … A European Journal, 2023 - Wiley Online Library
Corroles have attracted increasing research interests in recent decades owing to their
unique properties over porphyrins. However, the relatively inefficient and tedious synthetic …

Facile Peptide Macrocyclization and Multifunctionalization via Cyclen Installation

TL Cheung, LKB Tam, WS Tam, L Zhang… - Small …, 2024 - Wiley Online Library
Cyclen‐peptide bioconjugates are usually prepared in multiple steps that require individual
preparation and purification of the cyclic peptide and hydrophilic cyclen derivatives. An …

Bimetallic porphyrin PET radiotracers for Low-Dose MRI contrast enhancement

C Xie, X Li, L Zhang, HF Chau, W Thor, WS Tam… - Chemical Engineering …, 2024 - Elsevier
In medical imaging, concerns over the risks associated with imaging agents have been
consistently raised by doctors and patients, and ongoing efforts are being made to …

Nuclear Localization Signal Enhances the Targeting and Therapeutic Efficacy of a Porphyrin-Based Molecular Cargo: A Systemic In Vitro and Ex Vivo Evaluation

N Kumar, AK Sharma, M Guleria, SB Shelar… - Molecular …, 2024 - ACS Publications
The objective of the present work was to evaluate the potential of a nuclear localization
signal (NLS) toward facilitating intracellular delivery and enhancement in the therapeutic …

Near‐Infrared and Visible Dual‐Emitting Peptide by Modular Assembly of Nitrobenzoxadiazole and Neodymium Complexes

YH Yeung, HF Chau, HY Kai, W Zhou… - Advanced Optical …, 2024 - Wiley Online Library
The synthetic difficulty of target‐specific lanthanide complexes, despite their unique
characteristics, limits their use in in vitro/in vivo studies and biomedical applications. With …

Multifunctional porphyrin-ionic liquid aggregate for highly sensitive electrochemical detection of protein

P Ling, X Sun, X Gao, L Wang, P Yang, F Gao - Talanta, 2023 - Elsevier
Herein, this paper describes a novel label-free and extensibility electrochemical sensing
platform based on porphyrin-ionic liquid (Por-IL) aggregate for the detection of antibody. The …