The stimulator of interferon genes (STING) cellular signaling pathway is a promising target
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …

The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants
and “anatomical escape” characteristics threaten the effectiveness of current coronavirus …

An improved understanding of human T cell-mediated immunity in COVID-19 is important for
optimizing therapeutic and vaccine strategies. Experience with influenza shows that …

CD4+ T cells reactive against SARS-CoV-2 can be found in unexposed individuals, and
these are suggested to arise in response to common cold coronavirus (CCCoV) infection …

Owing to their capacity to rapidly spread across the population, airborne pathogens
represent a significant risk to global health. Indeed, several of the past major global …

To better understand primary and recall T cell responses during coronavirus disease 2019
(COVID-19), it is important to examine unmanipulated severe acute respiratory syndrome …

Cross-reactive CD4+ T cells that recognize severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are more commonly detected in the peripheral blood of unexposed …

SARS-CoV-2 causes a spectrum of COVID-19 disease, the immunological basis of which
remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or …

INTRODUCTION Current influenza vaccines must be refreshed annually to address constant
mutations of viral hemagglutinin (HA) and neuraminidase (NA) genes because the vaccines …