Background Genetic polymorphism is suggested to be associated with human physical
performance. The angiotensin I-converting enzyme insertion/deletion (ACE I/D) …

Understanding the genetic architecture of athletic performance is an important step in the
development of methods for talent identification in sport. Research concerned with …

The response to exercise training (trainability) has been shown to have a strong heritable
component. There is growing evidence suggesting that traits such as trainability do not only …

The ability of skeletal muscles to produce force at a high velocity, which is crucial for success
in power and sprint performance, is strongly influenced by genetics and without the …

Background To date, studies investigating the association between ACTN3 R577X and ACE
I/D gene variants and elite sprint/power performance have been limited by small cohorts …

Over the last couple of decades, research has focused on attempting to understand the
genetic influence on sports performance. This has led to the identification of a number of …

This chapter is devoted to the role of genetic variation and gene-exercise interactions in the
biology of adaptation to exercise. There is evidence from genetic epidemiology research that …

A common null polymorphism (rs1815739; R577X) in the gene that codes for α-actinin-3
(ACTN3) has been related to different aspects of exercise performance. Individuals who are …

There is compelling evidence that genetic factors influence several phenotype traits related
to physical performance and training response as well as to elite athletic status. Previous …

α-Actinin-3 deficiency occurs in approximately 16% of the global population due to
homozygosity for a common nonsense polymorphism in the ACTN3 gene. Loss of α-actinin …