Applications of vibrational spectroscopy for analysis of connective tissues

W Querido, S Kandel, N Pleshko - Molecules, 2021 - mdpi.com
Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …

Stem cells and extrusion 3D printing for hyaline cartilage engineering

O Messaoudi, C Henrionnet, K Bourge, D Loeuille… - Cells, 2020 - mdpi.com
Hyaline cartilage is deficient in self-healing properties. The early treatment of focal cartilage
lesions is a public health challenge to prevent long-term degradation and the occurrence of …

Machine learning estimation of tissue optical properties

BH Hokr, JN Bixler - Scientific Reports, 2021 - nature.com
Dynamic, in vivo measurement of the optical properties of biological tissues is still an elusive
and critically important problem. Here we develop a technique for inverting a Monte Carlo …

Visible and near-infrared spectroscopy enables differentiation of normal and early osteoarthritic human knee joint articular cartilage

A Linus, P Tanska, JK Sarin, E Nippolainen… - Annals of Biomedical …, 2023 - Springer
Osteoarthritis degenerates cartilage and impairs joint function. Early intervention
opportunities are missed as current diagnostic methods are insensitive to early tissue …

[HTML][HTML] Optical imaging of dynamic collagen processes in health and disease

LE Iannucci, CS Dranoff, MA David… - Frontiers in Mechanical …, 2022 - frontiersin.org
Collagen is a major structural component of nearly every tissue in the human body, whose
hierarchical organization imparts specific mechanical properties and defines overall tissue …

Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands

I Kafian-Attari, E Nippolainen, F Bergmann… - Biomedical Optics …, 2023 - opg.optica.org
There is increasing research on the potential application of diffuse optical spectroscopy and
hyperspectral imaging for characterizing the health of the connective tissues, such as …

Diffuse reflectance spectroscopy of the cartilage tissue in the fourth optical window

DA Nazarov, GM Denisenko, GS Budylin… - Biomedical Optics …, 2023 - opg.optica.org
Studies of the optical properties of biological tissues in the infrared range have
demonstrated significant potential for diagnostic tasks. One of the insufficiently explored …

Neural network‐based optimization of sub‐diffuse reflectance spectroscopy for improved parameter prediction and efficient data collection

J An, Q Zhang, L Zhang, C Liu, D Liu… - Journal of …, 2023 - Wiley Online Library
In this study, a general and systematical investigation of sub‐diffuse reflectance
spectroscopy is implemented. A Gegenbauer‐kernel phase function‐based Monte Carlo is …

Articular cartilage optical properties in the near-infrared (NIR) spectral range vary with depth and tissue integrity

B Khan, I Kafian-Attari, E Nippolainen… - Biomedical Optics …, 2021 - opg.optica.org
Optical properties of biological tissues in the NIR spectral range have demonstrated
significant potential for in vivo diagnostic applications and are critical parameters for …

Raman Spectroscopy and Machine Learning Enables Estimation of Articular Cartilage Structural, Compositional, and Functional Properties

E Shehata, E Nippolainen, R Shaikh… - Annals of Biomedical …, 2023 - Springer
Objective To differentiate healthy from artificially degraded articular cartilage and estimate its
structural, compositional, and functional properties using Raman spectroscopy (RS). Design …