[HTML][HTML] The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies

M Butnariu, C Quispe, J Herrera-Bravo, P Helon… - Biomedicine & …, 2022 - Elsevier
Thymoquinone (TQ) is a secondary metabolite found in abundance in very few plant species
including Nigella sativa L., Monarda fistulosa L., Thymus vulgaris L. and Satureja montana …

Enhanced efficacy and bioavailability of thymoquinone using nanoliposomal dosage form

MR Mohammadabadi, MR Mozafari - Journal of drug delivery science and …, 2018 - Elsevier
Thymoquinone (TQ) is the bioactive constituent of the volatile oil of different herbs and a
phytochemical constituent of Nigella sativa, cumin and some other herbs. It can modulate …

Evaluation of carum-loaded niosomes on breast cancer cells: Physicochemical properties, in vitro cytotoxicity, flow cytometric, DNA fragmentation and cell migration …

M Barani, M Mirzaei, M Torkzadeh-Mahani… - Scientific reports, 2019 - nature.com
Thymoquinone (TQ), a phytochemical compound found in Carum carvil seeds (C. carvil),
has a lot of applications in medical especially cancer therapy. However, TQ has a …

Aqueous solubility and degradation kinetics of the phytochemical anticancer thymoquinone; probing the effects of solvents, pH and light

JMM Salmani, S Asghar, H Lv, J Zhou - Molecules, 2014 - mdpi.com
Thymoquinone (TQ) is a potent anticancer phytochemical with confirmed in vitro efficacy. Its
clinical use has not yet established, and very few reports have documented its formulation …

Structural Characterization, Antimicrobial Activity, and In Vitro Cytotoxicity Effect of Black Seed Oil

SJ Mohammed, HHH Amin, SB Aziz… - Evidence‐Based …, 2019 - Wiley Online Library
This study was aimed to investigate the structure of bioactive components of black seed oil
(BSO) and their antimicrobial and cytotoxic effects. Initially, the structural examination was …

Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration

SI Abdelwahab, BY Sheikh, MME Taha… - International journal …, 2013 - Taylor & Francis
Background Nanostructured lipid carriers (NLCs), composed of solid and liquid lipids, and
surfactants are potentially good colloidal drug carriers. Thymoquinone is the main bioactive …

Spanlastics as an efficient delivery system for the enhancement of thymoquinone anticancer efficacy: Fabrication and cytotoxic studies against breast cancer cell lines

E Alaaeldin, M Mostafa, HF Mansour… - Journal of Drug Delivery …, 2021 - Elsevier
Thymoquinone (TQ), a pleiotropic compound isolated from the seeds of Nigella sativa has a
great potential as a chemotherapeutic agent against several cancers. However, its limited …

HPLC Quantification of Thymoquinone Extracted from Nigella sativa L. (Ranunculaceae) Seeds and Antibacterial Activity of Its Extracts against Bacillus Species

N Habib, S Choudhry - Evidence‐Based Complementary and …, 2021 - Wiley Online Library
The medicinal importance of Nigella sativa seeds for treating various ailments is portrayed
by its traditional uses. Owing to its immense pharmacological importance, the thymoquinone …

Remote loading of curcumin-in-modified β-cyclodextrins into liposomes using a transmembrane pH gradient

F Odeh, H Nsairat, W Alshaer, S Alsotari, R Buqaien… - RSC …, 2019 - pubs.rsc.org
Curcumin (CRM) is a natural polyphenol with antioxidative, anti-inflammatory, and
anticancer therapeutic properties. However, CRM therapeutic potential is limited by low …

[HTML][HTML] Solvent based optimization for extraction and stability of thymoquinone from Nigella sativa Linn. and its quantification using RP-HPLC

MS Iqbal, A Ahmad, B Pandey - Physiology and Molecular Biology of …, 2018 - Springer
The Nigella sativa pharmacological properties are mainly ascribed to its volatile oil, of which
thymoquinone is an important bioactive component. Surprisingly, till date, no standard …