Diagnosis and treatment of invasive candidiasis

N Barantsevich, E Barantsevich - Antibiotics, 2022 - mdpi.com
Candida species, belonging to commensal microbial communities in humans, cause
opportunistic infections in individuals with impaired immunity. Pathogens encountered in …

Candida parapsilosis: from genes to the bedside

R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - Am Soc Microbiol
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

Clinical practice guideline for the management of candidiasis: 2016 update by the Infectious Diseases Society of America

PG Pappas, CA Kauffman, DR Andes… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients

F Tissot, S Agrawal, L Pagano, G Petrikkos… - …, 2016 - pmc.ncbi.nlm.nih.gov
The European Conference on Infections in Leukemia (ECIL) provides recommendations for
diagnostic strategies and prophylactic, pre-emptive or targeted therapy strategies for various …

Epidemiology and Outcomes of Invasive Candidiasis Due to Non-albicans Species of Candida in 2,496 Patients: Data from the Prospective Antifungal Therapy …

MA Pfaller, DR Andes, DJ Diekema, DL Horn… - PloS one, 2014 - journals.plos.org
This analysis describes the epidemiology and outcomes of invasive candidiasis caused by
non-albicans species of Candida in patients enrolled in the Prospective Antifungal Therapy …

The quiet and underappreciated rise of drug-resistant invasive fungal pathogens

A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …

8th European Conference on Infections in Leukaemia: 2020 guidelines for the diagnosis, prevention, and treatment of invasive fungal diseases in paediatric patients …

AH Groll, D Pana, F Lanternier, A Mesini… - The Lancet …, 2021 - thelancet.com
Paediatric patients with cancer and those undergoing allogeneic haematopoietic cell
transplantation have an increased susceptibility to invasive fungal diseases. In addition to …

Candidemia: evolution of drug resistance and novel therapeutic approaches

AM Tortorano, A Prigitano, G Morroni… - Infection and Drug …, 2021 - Taylor & Francis
Candidemia and invasive candidiasis are the most common healthcare-associated invasive
fungal infections, with a crude mortality rate of 25–50%. Candida albicans remains the most …

Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus

SS Gonçalves, ACR Souza, A Chowdhary, JF Meis… - Mycoses, 2016 - Wiley Online Library
The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …

Decreased echinocandin susceptibility in Candida parapsilosis causing candidemia and emergence of a pan-echinocandin resistant case in China

Y Ning, M Xiao, DS Perlin, Y Zhao, M Lu… - Emerging Microbes & …, 2023 - Taylor & Francis
Candida parapsilosis is becoming a predominant non-albicans cause of invasive
candidiasis (IC). Echinocandins are the preferred choice for IC treatment and prophylaxis …