Large-scale data acquisition and analysis are often required in the successful
implementation of the design, build, test, and learn (DBTL) cycle in biosystems design …

To perform their computational function, genetic circuits change states through a symphony
of genetic parts that turn regulator expression on and off. Debugging is frustrated by an …

Optimising the function of a protein of length N amino acids by directed evolution involves
navigating a 'search space'of possible sequences of some 20 N. Optimising the expression …

Cell-free genetically encoded biosensors have been developed to detect small molecules
and nucleic acids, but they have yet to be reliably engineered to detect proteins. Here we …

One of the optimization strategies of an artificial biosynthetic metabolic flux with a
multienzyme pathway is when the enzyme concentrations are present at the appropriate …

合成生物学的迅猛发展给包括药物和化学品在内的生物制造带来了强劲动力.
它助力生物合成关键元件的挖掘, 丰富了智能生物制造所必需的基础(催化) 元件库; …

Plant-based biopreparations are reasonably priced and are devoid of viral, prion and
endotoxin contaminants. However, synthesizing these natural plant products by chemical …

Biological systems are excellent sensing platforms, able to specifically detect a diverse array
of chemical and biomolecular stimuli in their environment and respond rapidly and …

Synthetic biology, which combines tools from engineering, molecular biology and
computation, aims to explore the biological systems available in nature and engineer new …