Allergen immunotherapy is a form of therapeutic vaccination for established IgE-mediated
hypersensitivity to common allergen sources such as pollens, house dust mites and the …

The 2020 Focused Updates to the Asthma Management Guidelines: A Report from the
National Asthma Education and Prevention Program Coordinating Committee Expert Panel …

IgG4 is the least abundant subclass of IgG in human serum and has unique functional
features. IgG4 is largely unable to activate antibody-dependent immune effector responses …

The exponential growth of precision diagnostic tools, including omic technologies, molecular
diagnostics, sophisticated genetic and epigenetic editing, imaging and nano‐technologies …

Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease
affecting more than 30% of the population. Exposure to even minute quantities of allergens …

The role of innate immune cells in allergen immunotherapy that confers immune tolerance to
the sensitizing allergen is unclear. Here, we report a role of interleukin-10-producing type 2 …

Food allergy is a pathological, potentially deadly, immune reaction triggered by normally
innocuous food protein antigens. The prevalence of food allergies is rising and the standard …

Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …

Background The prevalence of peanut allergy among children in Western countries has
doubled in the past 10 years, and peanut allergy is becoming apparent in Africa and Asia …

Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human
serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ …