A systematic review of the neuropathology and memory decline induced by monosodium glutamate in the Alzheimer's disease-like animal model

SS Ankul, L Chandran, S Anuragh… - Frontiers in …, 2023 - frontiersin.org
This systematic review analyzes monosodium glutamate (MSG) in the Alzheimer's disease-
like condition to enhance translational research. Our review seeks to understand how MSG …

Influence of glutamatergic and GABAergic neurotransmission on obstructive sleep apnea

P Kaczmarski, M Sochal, D Strzelecki… - Frontiers in …, 2023 - frontiersin.org
Glutamate and γ-aminobutyric acid (GABA) are the two main neurotransmitters in the human
brain. The balance between their excitatory and inhibitory functions is crucial for maintaining …

[HTML][HTML] Arbutin-modified microspheres prevent osteoarthritis progression by mobilizing local anti-inflammatory and antioxidant responses

J Jin, Y Liu, C Jiang, Y Shen, G Chu, C Liu, L Jiang… - Materials Today Bio, 2022 - Elsevier
Osteoarthritis (OA) is a common degenerative joint disease worldwide and currently there is
no effective strategy to stop its progression. It is known that oxidative stress and inflammation …

[HTML][HTML] Experimental evidence of the neurotoxic effect of monosodium glutamate in adult female Sprague Dawley rats: The potential protective role of Zingiber …

SA El-Hashash, MA El-Sakhawy, HSE Eldamaty… - Saudi Journal of …, 2023 - Elsevier
Strategies to prevent the health abnormalities associated with the extensive use of MSG
(monosodium glutamate) as a flavoring booster are badly needed. The current study was …

Arbutin ameliorates hyperglycemia, dyslipidemia and oxidative stress and modulates adipocytokines and PPARγ in high-fat diet/streptozotocin-induced diabetic rats

MS Abduh, MA Alzoghaibi, AM Alzoghaibi… - Life Sciences, 2023 - Elsevier
Arbutin is a glycosylated hydroquinone with antioxidant and anti-hyperglycemia effects.
However, its beneficial effects in type 2 diabetes (T2D) were not clarified. This study …

The Role of Monosodium Glutamate (MSG) in Epilepsy and other Neurodegenerative Diseases: Phytochemical-based Therapeutic Approa-ches and Mechanisms

M Singh, SP Panda - Current Pharmaceutical Biotechnology, 2024 - ingentaconnect.com
Epilepsy is a common neurological disease affecting 50 million individuals worldwide, and
some forms of epilepsy do not respond to available treatments. Overactivation of the …

[PDF][PDF] Pharmacological Aspects of a Bioactive Compound Arbutin: A Comprehensive Review

M Bhalla, R Mittal, M Kumar… - Biointerface Res. Appl …, 2022 - academia.edu
Over the past few decades, researchers emphasized herbal medicines as an alternative
therapeutic approach due to the high success rate of developing a new drug from a natural …

[HTML][HTML] Targeting JAK2/STAT3, NLRP3/Caspase-1, and PK2/PKR2 Pathways with Arbutin Ameliorates Lead Acetate-Induced Testicular Injury in Rats

HH Arab, SE Alsufyani, AM Ashour, AM Gad… - Pharmaceuticals, 2024 - mdpi.com
The reproductive system of males is adversely impacted by lead (Pb), a toxic heavy metal.
The present study examined arbutin, a promising hydroquinone glycoside, for its potential …

The protective effect of arbutin against potassium bromate‐induced oxidative damage in the rat brain

HT Akkoyun, A Uyar… - … of Biochemical and …, 2023 - Wiley Online Library
This study aimed to investigate the protective effects of arbutin (ARB) against brain injury
induced in rats with potassium bromate (KBrO3). The rats were divided into four groups as …

Efficacy of acupuncture combined with traditional Chinese herbal for primary epilepsy patients with cognitive impairment: A protocol for systematic review and meta …

H Xue, L Zeng, H He, D Xu - PloS one, 2024 - journals.plos.org
Background Epilepsy is a common and serious chronic neurological disorder, and some
patients suffer from cognitive dysfunction. We aim to assess the efficacy and safety of …