Natural marine products: Anti-colorectal cancer in vitro and in vivo

N Han, J Li, X Li - Marine drugs, 2022 - mdpi.com
Colorectal cancer, a malignant tumor with high mortality, has a poor prognosis due to drug
resistance and toxicity in clinical surgery and chemotherapy. Thus, finding safer and more …

Marine biome-derived secondary metabolites, a class of promising antineoplastic agents: A systematic review on their classification, mechanism of action and future …

A Sugumaran, R Pandiyan, P Kandasamy… - Science of the Total …, 2022 - Elsevier
Cancer is one of the most deadly diseases on the planet. Over the past decades, numerous
antineoplastic compounds have been discovered from natural resources such as medicinal …

Biotransformation of oleanane and ursane triterpenic acids

NA Luchnikova, VV Grishko, IB Ivshina - Molecules, 2020 - mdpi.com
Oleanane and ursane pentacyclic triterpenoids are secondary metabolites of plants found in
various climatic zones and regions. This group of compounds is highly attractive due to their …

Drug discovery inspired by bioactive small molecules from nature

S Kim, SW Lim, J Choi - Animal Cells and Systems, 2022 - Taylor & Francis
Natural products (NPs) have greatly contributed to the development of novel treatments for
human diseases such as cancer, metabolic disorders, and infections. Compared to synthetic …

The convergence of in silico approach and nanomedicine for efficient cancer treatment; in vitro investigations on curcumin loaded multifunctional graphene oxide …

F Paknia, H Mohabatkar, M Ahmadi-Zeidabadi… - Journal of Drug Delivery …, 2022 - Elsevier
The development of multifunctional nano-carriers with the ability of stimuli responsive
controlled drug release can address many of the challenges of current cancer therapies …

Holothuria triterpene glycosides: a comprehensive guide for their structure elucidation and critical appraisal of reported compounds

YE Puspitasari, T De Bruyne, K Foubert… - Phytochemistry …, 2022 - Springer
Sea cucumbers or holothurians are marine invertebrates, belonging to the phylum
Echinodermata (kingdom Animalia). In Asia, they are commonly used as food, while they are …

[PDF][PDF] LC-HRMS based approach for identification and quantification analysis of chemical constituents of sea cucumbers from aegean sea-their cytotoxic and antiviral …

NB Sarikahya, GS Okkali, D Gunay, AC Goren… - Nat. Prod, 2022 - acgpubs.org
Figure S1: Collecting area of sea cucumbers 2 Table S1: Mass parameters and linear
regression equation of compounds. 3 Figure S2: Viability of S. regalis against the cell lines 4 …

Chilean sea cucumber: New potential source of biomolecules with high nutritional value and cytotoxic activity

F Silva-Ramírez, C Aguirre, R Riveros… - Journal of Food …, 2024 - Elsevier
Sea cucumbers are important sources of human food and pharmacological compounds.
However, few studies have evaluated the potential differences between the sexes or organs …

Nutritional Value and Biological Activities of Sea Cucumber Holothuria scabra Cultured in the Open Pond System

DA Wulandari, N Gustini, T Murniasih… - Journal of Aquatic …, 2022 - Taylor & Francis
The aim of this study was to investigate the production of H. scabra in an open pond culture
system and to evaluate the nutritional value and biological activities. H scabra in this study …

Evaluation of cytotoxic, apoptotic effects and phenolic compounds of sea cucumberHolothuria tubulosa (Gmelin, 1791) extracts

M Alper, M Güneş - Turkish Journal of Veterinary & Animal …, 2020 - journals.tubitak.gov.tr
This study aimed to investigate the potential cytotoxic effects and phenolic contents of
aqueous (HTS) and methanolic (HTM) extracts of Holothuria tubulosa gathered from Muğla …