[HTML][HTML] The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance

W Dermauw, T Van Leeuwen - Insect biochemistry and molecular biology, 2014 - Elsevier
About a 100 years ago, the Drosophila white mutant marked the birth of Drosophila genetics.
The white gene turned out to encode the first well studied ABC transporter in arthropods …

[HTML][HTML] Impact of environment on mosquito response to pyrethroid insecticides: facts, evidences and prospects

TE Nkya, I Akhouayri, W Kisinza, JP David - Insect biochemistry and …, 2013 - Elsevier
By transmitting major human diseases such as malaria, dengue fever and filariasis,
mosquito species represent a serious threat worldwide in terms of public health, and pose a …

g: Profiler—a web server for functional interpretation of gene lists (2016 update)

J Reimand, T Arak, P Adler, L Kolberg… - Nucleic acids …, 2016 - academic.oup.com
Functional enrichment analysis is a key step in interpreting gene lists discovered in diverse
high-throughput experiments. g: Profiler studies flat and ranked gene lists and finds …

Contributions of cuticle permeability and enzyme detoxification to pyrethroid resistance in the major malaria vector Anopheles gambiae

GA Yahouédo, F Chandre, M Rossignol, C Ginibre… - Scientific reports, 2017 - nature.com
To tackle the problem of insecticide resistance, all resistance mechanisms need to be
studied. This study investigated the involvement of the cuticle in pyrethroid resistance in a …

Insect ATP-binding cassette (ABC) transporters: roles in xenobiotic detoxification and Bt insecticidal activity

C Wu, S Chakrabarty, M Jin, K Liu, Y Xiao - International journal of …, 2019 - mdpi.com
ATP-binding cassette (ABC) transporters, a large class of transmembrane proteins, are
widely found in organisms and play an important role in the transport of xenobiotics. Insect …

[PDF][PDF] Effects of microclimatic changes caused by deforestation on the survivorship and reproductive fitness of Anopheles gambiae in western Kenya highlands

YA Afrane, G Zhou, BW Lawson… - American Journal of …, 2006 - academia.edu
Land use changes have been suggested as one of the causes for malaria epidemics in the
African highlands. This study investigated the effects of deforestation-induced changes in …

Associated patterns of insecticide resistance in field populations of malaria vectors across Africa

PA Hancock, A Wiebe, KA Gleave… - Proceedings of the …, 2018 - National Acad Sciences
The development of insecticide resistance in African malaria vectors threatens the continued
efficacy of important vector control methods that rely on a limited set of insecticides. To …

Structure and function of cytochrome P450S in insect adaptation to natural and synthetic toxins: insights gained from molecular modeling

MA Schuler, MR Berenbaum - Journal of chemical ecology, 2013 - Springer
Over evolutionary time, insect herbivores have adapted to the presence of natural toxins and
more recently to synthetic insecticides in or on the plants they consume. Biochemical …

A systemic study of indoxacarb resistance in Spodoptera litura revealed complex expression profiles and regulatory mechanism

L Shi, Y Shi, Y Zhang, X Liao - Scientific reports, 2019 - nature.com
The tobacco cutworm, Spodoptera litura, is an important pest of crop and vegetable plants
worldwide, and its resistance to insecticides have quickly developed. However, the …

Multiple cytochrome P450 genes: conferring high levels of permethrin resistance in mosquitoes, Culex quinquefasciatus

T Yang, T Li, X Feng, M Li, S Liu, N Liu - Scientific Reports, 2021 - nature.com
Insecticides, especially pyrethroids, are the most important in the insect pest control and
preventing insect vector-borne human diseases. However, insect pests, including …