The presence of toxins is believed to be a major factor in the development of uremia in
patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Uremic …

Objectives: Rapid fluid resuscitation has become standard in sepsis care, despite “low-
quality” evidence and absence of guidelines for populations “at risk” for volume overload …

Fibroblast growth factor-23 (FGF-23) is a bone-derived hormone that activates FGFR/α-
Klotho binary complexes in the kidney renal tubules to regulate phosphate reabsorption and …

Occurrence of urosepsis is not uncommon following urinary tract infections (UTI). However,
there is a lack of evidence explaining the risk factors predisposing to urosepsis in patients …

Background End stage renal disease (ESRD) is increasing in the US, and these patients
demonstrate greater all-cause mortality, cardiovascular events, and hospitalization rates …

Patients with chronic kidney disease (CKD) are at high risk for developing critical illness and
for admission to intensive care units (ICU).'Critically ill CKD patients' frequently develop an …

Due to the potential risk of volume overload, physicians are hesitant to aggressively fluid-
resuscitate septic patients with end-stage renal disease (ESRD) on hemodialysis (HD) …

Objectives This study aims to examine the outcome of end-stage renal disease (ESRD)
patients admitted with sepsis to the intensive care unit (ICU). Design Single centre …

There is a range of medical conditions, which include acute organ failure, bacterial and viral
infection, and sepsis, that result in overactivation of the inflammatory response of the …

Background The infectious complications in hemodialysis patients are still among the main
reasons for their increased morbidity and mortality. The possible reasons behind this might …