Chitosan-based nanomaterials for drug delivery

J Li, C Cai, J Li, J Li, J Li, T Sun, L Wang, H Wu, G Yu - Molecules, 2018 - mdpi.com
This review discusses different forms of nanomaterials generated from chitosan and its
derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple …

Metal nanoclusters: novel probes for diagnostic and therapeutic applications

Y Tao, M Li, J Ren, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal nanoclusters, composed of several to a few hundred metal atoms, have received
worldwide attention due to their extraordinary physical and chemical characteristics …

Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation

W Gu, F Meng, R Haag, Z Zhong - Journal of controlled release, 2021 - Elsevier
The development of targeted nanomedicines for cancer therapy has been an utmost focus of
research across different fields including materials science, nanotechnology, biotechnology …

Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application

Z Song, Z Han, S Lv, C Chen, L Chen, L Yin… - Chemical Society …, 2017 - pubs.rsc.org
Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …

Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide

HX Wang, Z Song, YH Lao, X Xu… - Proceedings of the …, 2018 - National Acad Sciences
Effective and safe delivery of the CRISPR/Cas9 gene-editing elements remains a challenge.
Here we report the development of PEGylated nanoparticles (named P-HNPs) based on the …

Injectable graphene oxide/hydrogel-based angiogenic gene delivery system for vasculogenesis and cardiac repair

A Paul, A Hasan, HA Kindi, AK Gaharwar, VTS Rao… - ACS …, 2014 - ACS Publications
The objective of this study was to develop an injectable and biocompatible hydrogel which
can efficiently deliver a nanocomplex of graphene oxide (GO) and vascular endothelial …

Functional supramolecular polymers for biomedical applications

R Dong, Y Zhou, X Huang, X Zhu, Y Lu… - Advanced …, 2015 - Wiley Online Library
As a novel class of dynamic and non‐covalent polymers, supramolecular polymers not only
display specific structural and physicochemical properties, but also have the ability to …

Tumor acidity-sensitive polymeric vector for active targeted siRNA delivery

CY Sun, S Shen, CF Xu, HJ Li, Y Liu… - Journal of the …, 2015 - ACS Publications
Although surface PEGylation of siRNA vectors is effective for preventing protein adsorption
and thereby helps these vectors to evade the reticuloendothelial system (RES) in vivo, it also …

Supramolecular hydrogels: synthesis, properties and their biomedical applications

R Dong, Y Pang, Y Su, X Zhu - Biomaterials science, 2015 - pubs.rsc.org
As a novel class of three-dimensional (3D) hydrophilic cross-linked polymers,
supramolecular hydrogels not only display unique physicochemical properties (eg, water …

Functional polypeptide and hybrid materials: Precision synthesis via α-amino acid N-carboxyanhydride polymerization and emerging biomedical applications

C Deng, J Wu, R Cheng, F Meng, HA Klok… - Progress in Polymer …, 2014 - Elsevier
Polypeptides derived from naturally occurring α-amino acids have emerged as a unique and
versatile family of bio-inspired biomaterials that can be tailor-made for varying biomedical …