RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Due to the potential use as transfecting agents of nucleic acids (DNA or RNA), multivalent
cationic non-viral vectors have received special attention in the last decade. Much effort has …

The current review covers recent advances on development and investigation of cationic
surfactants containing imidazolium headgroup, which are being extensively investigated for …

Cationic liposome–nucleic acid (CL–NA) complexes, which form spontaneously, are a
highly modular gene delivery system. These complexes can be sterically stabilized via …

Self-assembled synthetic gene delivery systems represent the bottom-up approach to gene
delivery and gene silencing, in which scientists are designing novel cationic and procationic …

In recent years, substantial advances have been achieved in the design and synthesis of
nonviral gene vectors. However, lack of effective and biocompatible vectors still remains a …

In this study, we report the relationship between structure, self-assembly behavior and
antimicrobial activity of multicationic gemini surfactants and their successful use as …

A series of cationic silicon-based gemini surfactants (C m-PSi-C m) having different
hydrophobic chains length (m= 8, 10, 12, 14, 16, 18) were synthesized. Subsequently …

The toxicity of simple imidazolium and benzimidazolium salts started to be more and more
investigated in the last few years and was taken in consideration in the context of …

A new series of ester functionalized cationic gemini surfactants having different cationic
headgroups (ie piperidinium, pyrrolidinium, morpholinium and quaternary ammonium) have …