Near-infrared (NIR) spectroscopy is a powerful analytical method for rapid, non-destructive
and label-free assessment of biological materials. Compared to mid-infrared spectroscopy …

Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …

Osteoarthritis (OA) is a debilitating degenerative disease affecting multiple joint tissues,
including cartilage, bone, synovium, and adipose tissues. OA presents diverse clinical …

Recent research has been focusing on the generation of living personalized osteochondral
constructs for joint repair. Native articular cartilage has a zonal structure, which is not …

Osteoarthritis (OA) and chronic low back pain due to degenerative (intervertebral) disc
disease (DDD) are two of the major causes of disabilities worldwide, affecting hundreds of …

Conventional arthroscopic evaluation of articular cartilage is subjective and insufficient for
assessing early compositional and structural changes during the progression of post …

Introduction Assessment of cartilage integrity during arthroscopy is limited by the subjective
visual nature of the technique. To address this shortcoming in diagnostic evaluation of …

Osteoarthritis degenerates cartilage and impairs joint function. Early intervention
opportunities are missed as current diagnostic methods are insensitive to early tissue …

Objective To investigate the feasibility of near-infrared (NIR) spectroscopy (NIRS) for
evaluation of human articular cartilage biomechanical properties during arthroscopy. Design …

Osteoarthritis (OA) is the most common rheumatic disease, characterized by progressive
articular cartilage degradation. Raman spectroscopy (RS) has been recently proposed as a …