Brain metabolism in health, aging, and neurodegeneration

S Camandola, MP Mattson - The EMBO journal, 2017 - embopress.org
Brain cells normally respond adaptively to bioenergetic challenges resulting from ongoing
activity in neuronal circuits, and from environmental energetic stressors such as food …

Structural and functional brain changes related to different types of physical activity across the life span

C Voelcker-Rehage, C Niemann - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Physical activity has been shown to improve cognitive functioning. Research has largely
focused on cognitive facilitation by cardiovascular exercise in older adults. Only few studies …

Exercise, brain, and cognition across the life span

MW Voss, LS Nagamatsu… - Journal of applied …, 2011 - journals.physiology.org
This is a brief review of current evidence for the relationships between physical activity and
exercise and the brain and cognition throughout the life span in non-pathological …

Environment and brain plasticity: towards an endogenous pharmacotherapy

A Sale, N Berardi, L Maffei - Physiological reviews, 2014 - journals.physiology.org
Brain plasticity refers to the remarkable property of cerebral neurons to change their
structure and function in response to experience, a fundamental theoretical theme in the …

Neurogenesis, inflammation and behavior

RA Kohman, JS Rhodes - Brain, behavior, and immunity, 2013 - Elsevier
Before the 1990s it was widely believed that the adult brain was incapable of regenerating
neurons. However, it is now established that new neurons are continuously produced in the …

Physical activity and brain plasticity in late adulthood

KI Erickson, AG Gildengers… - Dialogues in clinical …, 2013 - Taylor & Francis
The human brain shrinks with advancing age, but recent research suggests that it is also
capable of remarkable plasticity, even in late life. In this review we summarize the research …

Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review

B Zimmerman, B Rypma, G Gratton… - …, 2021 - Wiley Online Library
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

Aerobic exercise as a tool to improve hippocampal plasticity and function in humans: practical implications for mental health treatment

A Kandola, J Hendrikse, PJ Lucassen… - Frontiers in human …, 2016 - frontiersin.org
Aerobic exercise (AE) has been widely praised for its potential benefits to cognition and
overall brain and mental health. In particular, AE has a potent impact on promoting the …

Brain glucose transporters: role in pathogenesis and potential targets for the treatment of Alzheimer's disease

L Szablewski - International Journal of Molecular Sciences, 2021 - mdpi.com
The most common cause of dementia, especially in elderly people, is Alzheimer's disease
(AD), with aging as its main risk factor. AD is a multifactorial neurodegenerative disease …

Enhancement of cognitive function in models of brain disease through environmental enrichment and physical activity

TYC Pang, AJ Hannan - Neuropharmacology, 2013 - Elsevier
This review will provide an overview of the non-drug based approaches that have been
demonstrated to enhance cognitive function of the compromised brain, primarily focussed on …