Application of rosmarinic acid with its derivatives in the treatment of microbial pathogens

ON Kernou, Z Azzouz, K Madani, P Rijo - Molecules, 2023 - mdpi.com
The emergence of the antimicrobial resistance phenomena on and the harmful
consequences of the use of antibiotics motivate the necessity of innovative antimicrobial …

Chemical composition, antioxidant, and anti-diabetic activities of ethyl acetate fraction of Stachys riederi var. japonica (Miq.) in streptozotocin-induced type 2 diabetic …

K Saravanakumar, S Park, AVA Mariadoss… - Food and Chemical …, 2021 - Elsevier
This work analysed the chemical composition, antioxidant, and enzyme inhibitory activities
of solvent extract (SJ-ME) and fractions (SJ-HF, SJ-EAF, and SJ-MF) of the Stachys riederi …

An Updated Overview of Synthetic α-glucosidase Inhibitors: Chemistry and Bioactivities

YS Cai, HX Xie, JH Zhang, Y Li, J Zhang… - Current Topics in …, 2023 - ingentaconnect.com
Diabetes mellitus (DM) is a critical global health issue, affecting nearly half a billion people
worldwide, with an increasing incidence rate and mortality. Type 2 diabetes is caused by the …

Synthesis and in vitro evaluation of chlorogenic acid amides as potential hypoglycemic agents and their synergistic effect with acarbose

N Cardullo, G Floresta, A Rescifina, V Muccilli… - Bioorganic …, 2021 - Elsevier
Type 2 Diabetes mellitus is a chronic disease considered one of the most severe global
health emergencies. Chlorogenic acid (1) has been shown to delay intestinal glucose …

Rosmarinic acid-grafted dextran/gelatin hydrogel as a wound dressing with improved properties: strong tissue adhesion, antibacterial, antioxidant and anti …

Y Yin, Q Xu, X Wei, Q Ma, D Li, J Zhao - Molecules, 2023 - mdpi.com
Designing a strong tissue adhesive and multifunctional hydrogel dressing for various skin
injuries is still a significant challenge. Based on the bioactive activities of rosmarinic acid …

Onosma aucheriana, O. frutescens, and O. sericea: Phytochemical profiling and biological activity

C Sarikurkcu, SS Sahinler, B Tepe - Industrial Crops and Products, 2020 - Elsevier
It is known that Onosma species are frequently used in the treatment of various ailments
such as bronchitis, strangury, leucoderma, abdominal pain and fever. The aim of this study …

Quinoa and Chia modulate AMPK/PPAR-ɣ signaling in high-fat diet–induced obesity rat model

NH Omran, AAZ El-Bahy, HTA Hosny… - Revista Brasileira de …, 2023 - Springer
Obesity is one of the principal reasons behind a wide range of metabolic diseases and
dramatic health complications. Recent studies shed the light on chia (Salvia hispanica L …

Onosma ambigens: Phytochemical composition, antioxidant and enzyme inhibitory activity

C Sarikurkcu, SS Sahinler, O Ceylan, B Tepe - Industrial Crops and …, 2020 - Elsevier
Due to their medical importance, the number of studies on the enlightenment of the
biological activities of Onosma species has been increasing over the years. In this study …

[HTML][HTML] Discovery of a novel class of rosmarinic acid derivatives as antibacterial agents: Synthesis, structure-activity relationship and mechanism of action

Y Wang, Z Liang, Y Cao, CH Hung, R Du… - Bioorganic …, 2024 - Elsevier
Twenty-seven rosmarinic acid derivatives were synthesized, among which compound RA-
N8 exhibited the most potent antibacterial ability. The minimum inhibition concentration of …

Effect of polyphenol, flavonoid, and saponin fractions from Thymus atlanticus on acute and chronic hyperlipidemia in mice

M Ramchoun, T Khouya, H Harnafi, C Alem… - Future journal of …, 2020 - Springer
Background Thymus atlanticus is an endemic plant of the Mediterranean region, which has
been used in the Moroccan mountain area to treat several diseases. This study aimed to …