The introduction of pathogens originating from Eurasia into the Americas during early
European contact has been associated with high mortality rates among Indigenous peoples …

Introduction Leprosy is a chronic infectious condition and the main cause of neuropathy that
occurs brought on by M. leprae. It is known that the biological characteristics of the human …

This perspective draws on the record of ancient pathogen genomes and microbiomes
illuminating patterns of infectious disease over the course of the Holocene in order to …

Objective Our objectives are twofold: to analyse the frequency of leprosy-related
pathological lesions in the cemetery of Sant Llàtzer Hospital (12th-18th c.); and to examine …

Mycobacterium leprae is classified into four SNP genotypes and 16 subtypes (from 1A to 4P)
that exhibit phylogeographical association reported from around the world. Among them …

Leprosy, one of the oldest recorded diseases in human history, remains prevalent in Asia,
Africa, and South America, with over 200,000 cases every year. 1, 2 Although ancient DNA …

Since life on earth developed, parasitic microbes have thrived. Increases in host numbers, or
the conquest of a new species, provide an opportunity for such a pathogen to enjoy, before …

Infectious diseases have had devastating impacts on human populations throughout history.
Still, the origins and past dynamics of human pathogens remain poorly understood. To …

Equine viral outbreaks have disrupted the socio-economic life of past human societies up
until the late 19th century and continue to be of major concern to the horse industry today …

This study investigates the efficacy of proteomic analysis of human remains to identify active
infections in the past through the detection of pathogens and the host response to infection …