The importance of linkers in the structure of PSMA ligands
AA Uspenskaya, EA Nimenko… - Current Medicinal …, 2022 - ingentaconnect.com
Cancer is one of the leading social problems of the modern world. Today prostate cancer is
the second leading cause of cancer deaths among men. Targeted drug delivery is widely …
the second leading cause of cancer deaths among men. Targeted drug delivery is widely …
Synthesis, 123I-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their …
LA Hasnowo, MS Larkina, E Plotnikov… - International Journal of …, 2023 - mdpi.com
Prostate-specific membrane antigen (PSMA) has been identified as a target for the
development of theranostic agents. In our current work, we describe the design and …
development of theranostic agents. In our current work, we describe the design and …
Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and Antiandrogens and Their Comparative Assessment with …
NY Zyk, AS Garanina, EA Plotnikova, AP Ber… - International Journal of …, 2023 - mdpi.com
Prostate cancer is the second most common cancer among men. We designed and
synthesized new ligands targeting prostate-specific membrane antigen and suitable for …
synthesized new ligands targeting prostate-specific membrane antigen and suitable for …
Synthesis and initial in vitro evaluation of PSMA-targeting ligands with a modified aromatic moiety at the lysine ε-nitrogen atom
NY Zyk, AP Ber, EA Nimenko, RR Shafikov… - Bioorganic & Medicinal …, 2022 - Elsevier
We report an improved series of ligands targeting prostate specific membrane antigen
(PSMA). The new compounds were designed by the introduction of changes in the structure …
(PSMA). The new compounds were designed by the introduction of changes in the structure …
Synthesis and organogelating behaviour of urea-and Fmoc-containing diphenylalanine based hexaamide
SA Petrov, AE Machulkin, RA Petrov… - Journal of Molecular …, 2021 - Elsevier
A new low molecular mass organic gelator based on tri-tert-butylates Glu-Urea-Lys and
Fmoc-capped di-L-Phe-containing hexaamide (tri-tert-butyl (10S, 13S, 31S, 35S)-10, 13 …
Fmoc-capped di-L-Phe-containing hexaamide (tri-tert-butyl (10S, 13S, 31S, 35S)-10, 13 …
Organic Chemistry in Russian Universities. Achievements of Recent Years
II Stoikov, IS Antipin, VA Burilov… - Russian Journal of …, 2024 - Springer
An overview of the main scientific achievements of Russian universities in the field of
organic chemistry over the period 2018–2023 is presented.
organic chemistry over the period 2018–2023 is presented.
Choice of the optimal synthetic approach for the polypeptide ligands of prostatic specific membrane antigen preparation
NY Zyk, SA Petrov, MV Zavertkina… - Mendeleev …, 2023 - Elsevier
Two alternative synthetic schemes involving solid-phase peptide synthesis steps for the
preparation of prostatic specific membrane antigen ligands based on Glu-Urea-Lys with …
preparation of prostatic specific membrane antigen ligands based on Glu-Urea-Lys with …
Cyclodextrin-drug conjugates-synthesis and study of their properties
AM Dušková - 2024 - dspace.cuni.cz
The diploma thesis deals with the synthesis of conjugates of the antitumor drug 5-
fluorouracil with cyclodextrins. Cyclodextrins are connected to the drug by linkers of different …
fluorouracil with cyclodextrins. Cyclodextrins are connected to the drug by linkers of different …