Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications-a review

B Grygiel-Górniak - Nutrition journal, 2014 - Springer
Peroxisome proliferator-activated receptors are expressed in many tissues, including
adipocytes, hepatocytes, muscles and endothelial cells; however, the affinity depends on the …

Crosstalk between peroxisome proliferator-activated receptor gamma and the canonical WNT/β-catenin pathway in chronic inflammation and oxidative stress during …

A Vallée, Y Lecarpentier - Frontiers in immunology, 2018 - frontiersin.org
Inflammation and oxidative stress are common and co-substantial pathological processes
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …

Aldehyde dehydrogenases and cell proliferation

G Muzio, M Maggiora, E Paiuzzi, M Oraldi… - Free Radical Biology and …, 2012 - Elsevier
Aldehyde dehydrogenases (ALDHs) oxidize aldehydes to the corresponding carboxylic
acids using either NAD or NADP as a coenzyme. Aldehydes are highly reactive aliphatic or …

Potential role of ANGPTL4 in the cross talk between metabolism and cancer through PPAR signaling pathway

L La Paglia, A Listì, S Caruso, V Amodeo… - PPAR …, 2017 - Wiley Online Library
The angiopoietin‐like 4 (ANGPTL4) protein belongs to a superfamily of secreted proteins
structurally related to factors modulating angiogenesis known as angiopoietins. At first …

The role of PPARγ in prostate cancer development and progression

A Hartley, I Ahmad - British Journal of Cancer, 2023 - nature.com
Advanced and metastatic prostate cancer is often incurable, but its dependency on certain
molecular alterations may provide the basis for targeted therapies. A growing body of …

Peroxisome proliferator-activated receptors and caloric restriction—common pathways affecting metabolism, health, and longevity

K Duszka, A Gregor, H Guillou, J König, W Wahli - Cells, 2020 - mdpi.com
Caloric restriction (CR) is a traditional but scientifically verified approach to promoting health
and increasing lifespan. CR exerts its effects through multiple molecular pathways that …

The highly unnatural fatty acid profile of cells in culture

PL Else - Progress in lipid research, 2020 - Elsevier
The fatty acid profile of cells in culture are unlike those of natural cells with twice the
monounsaturated (MUFA) and half the polyunsaturated fatty acids (PUFA) level (Mol%). This …

Effect of n-3 fatty acids on patients with advanced lung cancer: a double-blind, placebo-controlled study

C Finocchiaro, O Segre, M Fadda, T Monge… - British Journal of …, 2012 - cambridge.org
PUFA from fish oil appear to have anti-inflammatory and anti-oxidative effects and improve
nutritional status in cancer patients. With this as background, the aim of the present study …

Omega‐3 polyunsaturated fatty acids and lung cancer: nutrition or pharmacology?

OM Vega, S Abkenari, Z Tong, A Tedman… - Nutrition and …, 2021 - Taylor & Francis
Omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplements for chemoprevention of
different types of cancer including lung cancer has been investigated in recent years. ω-3 …

Seaweed lipids as nutraceuticals

L Mišurcová, J Ambrožová, D Samek - Advances in food and nutrition …, 2011 - Elsevier
Seaweeds are known as low-energy food. Despite low lipid content, ω-3 and ω-6
polyunsaturated fatty acids (PUFAs) introduce a significant part of seaweed lipids. PUFAs …