Metformin is the most widely prescribed drug to treat patients with type II diabetes, for whom
retrospective studies suggest that metformin may have anticancer properties. However, in …

Epilepsy is a chronic neurological disease characterized by recurrent seizures. Epilepsy is
observed as a well‐controlled disease by anti‐epileptic agents (AEAs) in about 69 …

BACKGROUND Type 2 diabetes mellitus (T2DM) is significantly increasing worldwide, and
the incidence of its complications is also on the rise. One of the main complications of T2DM …

The present study was designed to examine the possible neuroprotective and antiepileptic
effects of metformin (Metf) in a rat model of pentylenetetrazole (PTZ)-induced epilepsy and …

Background Available anti-seizure medications (ASMs) target the symptomatology of the
disease rather than any significant disease/epileptogenesis modifying actions. There are …

Background. Epilepsy is one of the common neurological illnesses which affects millions of
individuals globally. Although the majority of epileptic patients have a good response for the …

Epilepsy is a neurological disorder characterized by an enduring predisposition to generate
and aggravate epileptic seizures affecting around 1% of global population making it a …

Literature data on epidemiology, mechanisms of development, features of the course of
cognitive disorders in type 2 diabetes mellitus (T2DM), as well as prospects for their …

Sinapic acid (SA) is a naturally occurring carboxylic acid found in citrus fruits and cereals.
Recent studies have shown that SA has potential anti-seizure properties due to its anti …

PTZ is a convulsive agent that acts via selective blockage of GABA A receptor channels,
whereas 4-AP leads to a convulsive episode via blockage of K+ channels. However, the …