Peptide radicals and cation radicals in the gas phase
For about three decades, the chemistry of cation radicals derived from organic molecules
had received a major impetus from mass spectrometry. This was because cation radicals …
had received a major impetus from mass spectrometry. This was because cation radicals …
Application of electron transfer dissociation (ETD) for the analysis of posttranslational modifications
J Wiesner, T Premsler, A Sickmann - Proteomics, 2008 - Wiley Online Library
Despite major advantages in the field of proteomics, the analysis of PTMs still poses a major
challenge; thus far, preventing insights into the role and regulation of protein networks …
challenge; thus far, preventing insights into the role and regulation of protein networks …
Improved protein and PTM characterization with a practical electron-based fragmentation on Q-TOF instruments
JS Beckman, VG Voinov, M Hare… - Journal of the …, 2021 - ACS Publications
Electron-based dissociation (ExD) produces uncluttered mass spectra of intact proteins
while preserving labile post-translational modifications. However, technical challenges have …
while preserving labile post-translational modifications. However, technical challenges have …
Straightforward ladder sequencing of peptides using a Lys-N metalloendopeptidase
We introduce a method for sequencing peptides by mass spectrometry using a
metalloendopeptidase that cleaves proteins at the amino side of lysine (Lys-N). When …
metalloendopeptidase that cleaves proteins at the amino side of lysine (Lys-N). When …
Revealing ligand binding sites and quantifying subunit variants of noncovalent protein complexes in a single native top-down FTICR MS experiment
H Li, P Wongkongkathep, SL Van Orden… - Journal of The …, 2014 - ACS Publications
“Native” mass spectrometry (MS) has been proven to be increasingly useful for structural
biology studies of macromolecular assemblies. Using horse liver alcohol dehydrogenase …
biology studies of macromolecular assemblies. Using horse liver alcohol dehydrogenase …
Recent advancements, challenges, and practical considerations in the mass spectrometry-based analytics of protein biotherapeutics: A viewpoint from the biosimilar …
V Háda, A Bagdi, Z Bihari, SB Timári, Á Fizil… - … of pharmaceutical and …, 2018 - Elsevier
The extensive analytical characterization of protein biotherapeutics, especially of
biosimilars, is a critical part of the product development and registration. High-resolution …
biosimilars, is a critical part of the product development and registration. High-resolution …
Discrimination of leucine and isoleucine in peptides sequencing with Orbitrap Fusion mass spectrometer
An efficient approach to easy and reliable differentiation between isomeric leucine and
isoleucine in peptide sequencing utilizes multistage electron transfer dissociation and …
isoleucine in peptide sequencing utilizes multistage electron transfer dissociation and …
Electron transfer dissociation (ETD) of peptides containing intrachain disulfide bonds
The fragmentation chemistry of peptides containing intrachain disulfide bonds was
investigated under electron transfer dissociation (ETD) conditions. Fragments within the …
investigated under electron transfer dissociation (ETD) conditions. Fragments within the …
An EThcD-based method for discrimination of leucine and isoleucine residues in tryptic peptides
SS Zhokhov, SV Kovalyov, TY Samgina… - Journal of The …, 2017 - ACS Publications
An EThcD-based approach for the reliable discrimination of isomeric leucine and isoleucine
residues in peptide de novo sequencing procedure has been proposed. A multistage …
residues in peptide de novo sequencing procedure has been proposed. A multistage …
Identification of cyclic lipopeptides produced by Bacillus vallismortis R2 and their antifungal activity against Alternaria alternata
PK Kaur, N Joshi, IP Singh… - Journal of applied …, 2017 - academic.oup.com
Aim To identify the different antifungal biomolecules produced by isolate Bacillus vallismortis
R2 and analyse their effect on Alternaria alternata, a common pathogen causing black point …
R2 and analyse their effect on Alternaria alternata, a common pathogen causing black point …