Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives
T Lazarević, A Rilak, ŽD Bugarčić - European journal of medicinal chemistry, 2017 - Elsevier
Metallodrugs offer potential for unique mechanism of drug action based on the choice of the
metal, its oxidation state, the types and number of coordinated ligands and the coordination …
metal, its oxidation state, the types and number of coordinated ligands and the coordination …
The development of RAPTA compounds for the treatment of tumors
BS Murray, MV Babak, CG Hartinger… - Coordination Chemistry …, 2016 - Elsevier
Abstract Ruthenium (II)-arene RAPTA-type compounds have been extensively explored for
their medicinal properties. Herein a comprehensive review of this class of compounds is …
their medicinal properties. Herein a comprehensive review of this class of compounds is …
Direct synthesis of formic acid from carbon dioxide by hydrogenation in acidic media
S Moret, PJ Dyson, G Laurenczy - Nature communications, 2014 - nature.com
The chemical transformation of carbon dioxide into useful products becomes increasingly
important as CO2 levels in the atmosphere continue to rise as a consequence of human …
important as CO2 levels in the atmosphere continue to rise as a consequence of human …
Arene ruthenium complexes as anticancer agents
G Süss-Fink - Dalton Transactions, 2010 - pubs.rsc.org
Neutral or cationic arene ruthenium complexes providing both hydrophilic as well as
hydrophobic properties due to the robustness of the ruthenium–arene unit hold a high …
hydrophobic properties due to the robustness of the ruthenium–arene unit hold a high …
Metal-based antitumour drugs in the post genomic era
The discovery of new metal-based antitumour drugs, whether cisplatin derivatives or those
based on other metals, has been largely based on cell viability assays (IC50 values) and …
based on other metals, has been largely based on cell viability assays (IC50 values) and …
Coordination chemistry of 1, 3, 5-triaza-7-phosphaadamantane (PTA) and derivatives. Part II. The quest for tailored ligands, complexes and related applications
J Bravo, S Bolaño, L Gonsalvi, M Peruzzini - Coordination Chemistry …, 2010 - Elsevier
This review paper covers the recent developments (2004–2009) on the tailored synthetic
modifications and related coordination chemistry of the water-soluble cage-like …
modifications and related coordination chemistry of the water-soluble cage-like …
In vitro evaluation of rhodium and osmium RAPTA analogues: The case for organometallic anticancer drugs not based on ruthenium
A Dorcier, WH Ang, S Bolano, L Gonsalvi… - …, 2006 - ACS Publications
Reaction of the dimer [(η5-C5Me5) RhCl (μ2-Cl)] 2 with 2 or 4 equiv of the water-soluble
phosphine 1, 3, 5-triaza-7-phosphatricyclo [3.3. 1.1] decane (pta) affords [Rh (η5 …
phosphine 1, 3, 5-triaza-7-phosphatricyclo [3.3. 1.1] decane (pta) affords [Rh (η5 …
Ruthenium complexes: an emerging ground to the development of metallopharmaceuticals for cancer therapy
GLOBOCAN 2012 estimates 14.1 million new cancer cases and 8.2 million cancer-related
deaths worldwide. Cancer is rapidly becoming a major public health concern in India as …
deaths worldwide. Cancer is rapidly becoming a major public health concern in India as …
Anticancer activities of mononuclear ruthenium (II) coordination complexes
WM Motswainyana, PA Ajibade - Advances in Chemistry, 2015 - Wiley Online Library
Ruthenium compounds are highly regarded as potential drug candidates. The compounds
offer the potential of reduced toxicity and can be tolerated in vivo. The various oxidation …
offer the potential of reduced toxicity and can be tolerated in vivo. The various oxidation …
Synthesis, Characterization, and in Vitro Evaluation of Novel Ruthenium(II) η6-Arene Imidazole Complexes
CA Vock, C Scolaro, AD Phillips… - Journal of medicinal …, 2006 - ACS Publications
Ten complexes of general formula [Ru (η6-arene) Cl2 (L)],[Ru (η6-arene) Cl (L) 2][X], and
[Ru (η6-arene)(L) 3][X] 2 (η6-arene= benzene, p-cymene; L= imidazole, benzimidazole, N …
[Ru (η6-arene)(L) 3][X] 2 (η6-arene= benzene, p-cymene; L= imidazole, benzimidazole, N …