Gut microbiota dysbiosis in systemic lupus erythematosus: novel insights into mechanisms and promising therapeutic strategies

Q Pan, F Guo, Y Huang, A Li, S Chen, J Chen… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that was traditionally
thought to be closely related to genetic and environmental risk factors. Although treatment …

Safety and efficacy of fecal microbiota transplantation for autoimmune diseases and autoinflammatory diseases: A systematic review and meta-analysis

L Zeng, Y Deng, K Yang, J Chen, Q He… - Frontiers in …, 2022 - frontiersin.org
Objective To evaluate the safety and efficacy of fecal microbiota transplantation for
autoimmune diseases and autoinflammatory diseases. Methods Relevant literature was …

[HTML][HTML] GPR43 deficiency protects against podocyte insulin resistance in diabetic nephropathy through the restoration of AMPKα activity

J Lu, PP Chen, JX Zhang, XQ Li, GH Wang, BY Yuan… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Albuminuria is an early clinical feature in the progression of diabetic nephropathy
(DN). Podocyte insulin resistance is a main cause of podocyte injury, playing crucial roles by …

Human umbilical cord mesenchymal stem cells improve locomotor function in Parkinson's disease mouse model through regulating intestinal microorganisms

Z Sun, P Gu, H Xu, W Zhao, Y Zhou, L Zhou… - Frontiers in Cell and …, 2022 - frontiersin.org
Parkinson's disease (PD) is a progressive neurological disorder characterized by loss of
neurons that synthesize dopamine, and subsequent impaired movement. Umbilical cord …

Comparison of therapeutic effects of mesenchymal stem cells from umbilical cord and bone marrow in the treatment of type 1 diabetes

W Zhang, Q Ling, B Wang, K Wang, J Pang… - Stem cell research & …, 2022 - Springer
Background The therapeutic potential of mesenchymal stem cells (MSCs) in type 1 diabetes
(T1D) has been demonstrated in both preclinical and clinical studies. MSCs that have been …

Gut microbiota mediates the protective effects of traditional chinese medicine formula Qiong-Yu-Gao against cisplatin-induced acute kidney injury

YT Zou, J Zhou, JH Zhu, CY Wu, H Shen… - Microbiology …, 2022 - Am Soc Microbiol
Our previous study found that Qiong-Yu-Gao (QYG), a traditional Chinese medicine formula
derived from Rehmanniae Radix, Poria, and Ginseng Radix, has protective effects against …

[HTML][HTML] Gut microbiota dysbiosis in Chinese children with type 1 diabetes mellitus: An observational study

X Liu, YW Cheng, L Shao, SH Sun, J Wu… - World journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Gut microbiota dysbiosis is reportedly actively involved in autoimmune
diseases such as type 1 diabetes mellitus (T1DM). However, the alterations in the gut …

Human umbilical cord-derived mesenchymal stem cells ameliorate experimental colitis by normalizing the gut microbiota

F Yang, B Ni, Q Liu, F He, L Li, X Zhong… - Stem Cell Research & …, 2022 - Springer
Background Crohn's disease (CD) is a chronic non-specific inflammatory bowel disease.
Current CD therapeutics cannot fundamentally change the natural course of CD. Therefore …

[HTML][HTML] Regulated intestinal microbiota and gut immunity to ameliorate type 1 diabetes mellitus: A novel mechanism for stem cell-based therapy

SJ Zheng, Y Luo, JB Wang, XM Chen, Y Xu… - Biomedicine & …, 2024 - Elsevier
Although stem cell transplantation is an effective strategy in the treatment of type 1 diabetes
mellitus (T1DM), the mechanisms underlying its therapeutic effects remain unclear. We …

Effects of altitude on human oral microbes

F Liu, T Liang, Z Zhang, L Liu, J Li, W Dong, H Zhang… - AMB Express, 2021 - Springer
Human oral microbes play a vital role maintaining host metabolic homeostasis. The Qinghai-
Tibet Plateau is mainly characterized by a high altitude, dry, cold, and hypoxic environment …