[HTML][HTML] Epstein–Barr virus and multiple sclerosis

SS Soldan, PM Lieberman - Nature Reviews Microbiology, 2023 - nature.com
Epstein–Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-
established causal role in several cancers. Recent studies have provided compelling …

[HTML][HTML] Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis

T Schneider-Hohendorf, LA Gerdes… - Journal of Experimental …, 2022 - rupress.org
Epstein–Barr virus (EBV) infection precedes multiple sclerosis (MS) pathology and cross-
reactive antibodies might link EBV infection to CNS autoimmunity. As an altered anti-EBV T …

[HTML][HTML] The innate and T-cell mediated immune response during acute and chronic gammaherpesvirus infection

V Rex, R Zargari, M Stempel, S Halle… - Frontiers in Cellular …, 2023 - frontiersin.org
Immediately after entry into host cells, viruses are sensed by the innate immune system,
leading to the activation of innate antiviral effector mechanisms including the type I interferon …

[HTML][HTML] T cell-mediated immunity during Epstein–Barr virus infections in children

M Liu, R Wang, Z Xie - Infection, Genetics and Evolution, 2023 - Elsevier
Epstein–Barr virus (EBV) infection is extremely common worldwide, with approximately 90%
of adults testing positive for EBV antibodies. Human are susceptible to EBV infection, and …

[HTML][HTML] The dynamic role of immune checkpoint molecules in diagnosis, prognosis, and treatment of head and neck cancers

S Mestiri, DMA El-Ella, Q Fernandes, T Bedhiafi… - Biomedicine & …, 2024 - Elsevier
Head and neck cancer (HNC) is the sixth most common cancer type, accounting for
approximately 277,597 deaths worldwide. Recently, the Food and Drug Administration …

[HTML][HTML] KSHV infection of B cells primes protective T cell responses in humanized mice

N Caduff, L Rieble, M Böni, D McHugh… - Nature …, 2024 - nature.com
Kaposi sarcoma associated herpesvirus (KSHV) is associated with around 1% of all human
tumors, including the B cell malignancy primary effusion lymphoma (PEL), in which co …

[HTML][HTML] Prognostic impacts of soluble immune checkpoint regulators and cytokines in patients with SARS-CoV-2 infection

N Lee, S Jeong, K Jeon, MJ Park, W Song - Frontiers in Immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) has been a pandemic for the past two years.
Predicting patient prognosis is critical. Although immune checkpoints (ICs) were shown to be …

[HTML][HTML] Co-stimulatory molecules during immune control of Epstein Barr Virus infection

C Münz - Biomolecules, 2021 - mdpi.com
The Epstein Barr virus (EBV) is one of the prominent human tumor viruses, and it is
efficiently immune-controlled in most virus carriers. Cytotoxic lymphocytes strongly expand …

A metabolic dependency of EBV can be targeted to hinder B cell transformation

B Müller-Durovic, J Jäger, C Engelmann… - Science, 2024 - science.org
Following infection of B cells, Epstein Barr virus (EBV) engages host pathways that mediate
cell proliferation and transformation, contributing to the propensity of the virus to drive …

[HTML][HTML] Hub genes in non-small cell lung cancer regulatory networks

Q Ye, NL Guo - Biomolecules, 2022 - mdpi.com
There are currently no accurate biomarkers for optimal treatment selection in early-stage
non-small cell lung cancer (NSCLC). Novel therapeutic targets are needed to improve …