[HTML][HTML] Epstein–Barr virus and multiple sclerosis
SS Soldan, PM Lieberman - Nature Reviews Microbiology, 2023 - nature.com
Epstein–Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-
established causal role in several cancers. Recent studies have provided compelling …
established causal role in several cancers. Recent studies have provided compelling …
[HTML][HTML] Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis
T Schneider-Hohendorf, LA Gerdes… - Journal of Experimental …, 2022 - rupress.org
Epstein–Barr virus (EBV) infection precedes multiple sclerosis (MS) pathology and cross-
reactive antibodies might link EBV infection to CNS autoimmunity. As an altered anti-EBV T …
reactive antibodies might link EBV infection to CNS autoimmunity. As an altered anti-EBV T …
[HTML][HTML] The innate and T-cell mediated immune response during acute and chronic gammaherpesvirus infection
V Rex, R Zargari, M Stempel, S Halle… - Frontiers in Cellular …, 2023 - frontiersin.org
Immediately after entry into host cells, viruses are sensed by the innate immune system,
leading to the activation of innate antiviral effector mechanisms including the type I interferon …
leading to the activation of innate antiviral effector mechanisms including the type I interferon …
[HTML][HTML] T cell-mediated immunity during Epstein–Barr virus infections in children
M Liu, R Wang, Z Xie - Infection, Genetics and Evolution, 2023 - Elsevier
Epstein–Barr virus (EBV) infection is extremely common worldwide, with approximately 90%
of adults testing positive for EBV antibodies. Human are susceptible to EBV infection, and …
of adults testing positive for EBV antibodies. Human are susceptible to EBV infection, and …
[HTML][HTML] The dynamic role of immune checkpoint molecules in diagnosis, prognosis, and treatment of head and neck cancers
Head and neck cancer (HNC) is the sixth most common cancer type, accounting for
approximately 277,597 deaths worldwide. Recently, the Food and Drug Administration …
approximately 277,597 deaths worldwide. Recently, the Food and Drug Administration …
[HTML][HTML] KSHV infection of B cells primes protective T cell responses in humanized mice
N Caduff, L Rieble, M Böni, D McHugh… - Nature …, 2024 - nature.com
Kaposi sarcoma associated herpesvirus (KSHV) is associated with around 1% of all human
tumors, including the B cell malignancy primary effusion lymphoma (PEL), in which co …
tumors, including the B cell malignancy primary effusion lymphoma (PEL), in which co …
[HTML][HTML] Prognostic impacts of soluble immune checkpoint regulators and cytokines in patients with SARS-CoV-2 infection
N Lee, S Jeong, K Jeon, MJ Park, W Song - Frontiers in Immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) has been a pandemic for the past two years.
Predicting patient prognosis is critical. Although immune checkpoints (ICs) were shown to be …
Predicting patient prognosis is critical. Although immune checkpoints (ICs) were shown to be …
[HTML][HTML] Co-stimulatory molecules during immune control of Epstein Barr Virus infection
C Münz - Biomolecules, 2021 - mdpi.com
The Epstein Barr virus (EBV) is one of the prominent human tumor viruses, and it is
efficiently immune-controlled in most virus carriers. Cytotoxic lymphocytes strongly expand …
efficiently immune-controlled in most virus carriers. Cytotoxic lymphocytes strongly expand …
A metabolic dependency of EBV can be targeted to hinder B cell transformation
B Müller-Durovic, J Jäger, C Engelmann… - Science, 2024 - science.org
Following infection of B cells, Epstein Barr virus (EBV) engages host pathways that mediate
cell proliferation and transformation, contributing to the propensity of the virus to drive …
cell proliferation and transformation, contributing to the propensity of the virus to drive …
[HTML][HTML] Hub genes in non-small cell lung cancer regulatory networks
There are currently no accurate biomarkers for optimal treatment selection in early-stage
non-small cell lung cancer (NSCLC). Novel therapeutic targets are needed to improve …
non-small cell lung cancer (NSCLC). Novel therapeutic targets are needed to improve …