Current applications of nanoparticles in infectious diseases
For decades infections have been treated easily with drugs. However, in the 21st century,
they may become lethal again owing to the development of antimicrobial resistance …
they may become lethal again owing to the development of antimicrobial resistance …
Nanoparticle entry into cells; the cell biology weak link
G Griffiths, J Gruenberg, M Marsh, J Wohlmann… - Advanced Drug Delivery …, 2022 - Elsevier
Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …
Nanoantibiotics: Functions and properties at the nanoscale to combat antibiotic resistance
One primary mechanism for bacteria developing resistance is frequent exposure to
antibiotics. Nanoantibiotics (nAbts) is one of the strategies being explored to counteract the …
antibiotics. Nanoantibiotics (nAbts) is one of the strategies being explored to counteract the …
Nanocarriers for antibiotics: a promising solution to treat intracellular bacterial infections
N Abed, P Couvreur - International journal of antimicrobial agents, 2014 - Elsevier
In the field of antibiotherapy, intracellular infections remain difficult to eradicate mainly due to
the poor intracellular penetration of most of the commonly used antibiotics. Bacteria have …
the poor intracellular penetration of most of the commonly used antibiotics. Bacteria have …
Biocompatibility of nanomaterials and their immunological properties
TR Kyriakides, A Raj, TH Tseng, H Xiao… - Biomedical …, 2021 - iopscience.iop.org
Nanomaterials (NMs) have revolutionized multiple aspects of medicine by enabling novel
sensing, diagnostic, and therapeutic approaches. Advancements in processing and …
sensing, diagnostic, and therapeutic approaches. Advancements in processing and …
Bioinspired drug delivery strategies for repurposing conventional antibiotics against intracellular infections
Bacteria have developed a wealth of strategies to avoid and resist the action of antibiotics,
one of which involves pathogens invading and forming reservoirs within host cells. Due to …
one of which involves pathogens invading and forming reservoirs within host cells. Due to …
Advancements in prophylactic and therapeutic nanovaccines
Vaccines activate suitable immune responses to fight against diseases but can possess
limitations such as compromised efficacy and immunogenic responses, poor stability, and …
limitations such as compromised efficacy and immunogenic responses, poor stability, and …
Disassembling bacterial extracellular matrix with DNase-coated nanoparticles to enhance antibiotic delivery in biofilm infections
Infections caused by biofilm-forming bacteria are a major threat to hospitalized patients and
the main cause of chronic obstructive pulmonary disease and cystic fibrosis. There is an …
the main cause of chronic obstructive pulmonary disease and cystic fibrosis. There is an …
Application of nanoparticle technologies in the combat against anti-microbial resistance
Anti-microbial resistance is a growing problem that has impacted the world and brought
about the beginning of the end for the old generation of antibiotics. Increasingly, more …
about the beginning of the end for the old generation of antibiotics. Increasingly, more …
Enhanced permeability and retention-like extravasation of nanoparticles from the vasculature into tuberculosis granulomas in zebrafish and mouse models
The enhanced permeability and retention (EPR) effect is the only described mechanism
enabling nanoparticles (NPs) flowing in blood to reach tumors by a passive targeting …
enabling nanoparticles (NPs) flowing in blood to reach tumors by a passive targeting …