Multifactorial nature of human immunodeficiency virus disease: implications for therapy
AS Fauci - Science, 1993 - science.org
The immunopathogenic mechanisms underlying human immunodeficiency virus (HIV)
disease are extremely complex; the disease process is multifactorial with multiple …
disease are extremely complex; the disease process is multifactorial with multiple …
Diagnostic role of tests for T cell receptor (TCR) genes
E Hodges, MT Krishna, C Pickard… - Journal of clinical …, 2003 - jcp.bmj.com
Rapid advances in molecular biological techniques have made it possible to study disease
pathogenesis at a genomic level. T cell receptor (TCR) gene rearrangement is an important …
pathogenesis at a genomic level. T cell receptor (TCR) gene rearrangement is an important …
[图书][B] HIV and the pathogenesis of AIDS.
JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …
has been updated and expanded-now citing more than 2100 references (100 pages of the …
The innate biologies of adaptive antigen receptors
AC Hayday, P Vantourout - Annual Review of Immunology, 2020 - annualreviews.org
Nonclonal innate immune responses mediated by germ line–encoded receptors, such as
Toll-like receptors or natural killer receptors, are commonly contrasted with diverse …
Toll-like receptors or natural killer receptors, are commonly contrasted with diverse …
Early protective effect ofCCR-5A32 heterozygosity on HIV-1 disease progression: relationship with viral load
L Meyer, M Magierowska, JB Hubert, C Rouzioux… - Aids, 1997 - journals.lww.com
Objective: To determine the influence of heterozygosity for the A32 mutant CCR-5 allele on
HIV-1 disease progression. Design: HIV-1 disease progression and serum viral load were …
HIV-1 disease progression. Design: HIV-1 disease progression and serum viral load were …
Envelope glycoproteins of human immunodeficiency virus type 1: profound influences on immune functions
N Chirmule, S Pahwa - Microbiological reviews, 1996 - Am Soc Microbiol
Infection by human immunodeficiency virus type 1 (HIV-1) leads to progressive destruction
of the CD4+ T-cell subset, resulting in immune deficiency and AIDS. The specific binding of …
of the CD4+ T-cell subset, resulting in immune deficiency and AIDS. The specific binding of …
An approach to the validation of markers for use in AIDS clinical trials
Dr. Mildvan and coauthors have thoroughly reviewed and documented what is known about
the validation of surrogate markers for use in clinical trials. They have proposed a …
the validation of surrogate markers for use in clinical trials. They have proposed a …
Restricted Usage of T Cell Receptor Vα/Jα Gene Segments with Different Nucleotide but Identical Amino Acid Sequences in HLA-DR3+ Sarcoidosis Patients
J Grunewald, T Hultman, A Bucht, A Eklund… - Molecular Medicine, 1995 - Springer
Background Sarcoidosis is a granulomatous disease characterized by the accumulation of
activated T cells in the lungs. We previously showed that sarcoidosis patients expressing the …
activated T cells in the lungs. We previously showed that sarcoidosis patients expressing the …
Massive activation of immune cells with an intact T cell repertoire in acute human immunodeficiency virus syndrome
In 8 patients with symptomatic, acute primary infection with human immunodeficiency virus
(HIV), a dramatic and persistent decrease in CD4+ lymphocytes was seen, accompanied by …
(HIV), a dramatic and persistent decrease in CD4+ lymphocytes was seen, accompanied by …
The role of host immune responses in determining the outcome of HIV infection
M Westby, F Manca, AG Dalgleish - Immunology today, 1996 - Elsevier
The progression of disease following infection with human immunodeficiency virus (HIV)
correlates with an activated immune system and would appear to depend to some degree …
correlates with an activated immune system and would appear to depend to some degree …