[HTML][HTML] A review on exosomes application in clinical trials: perspective, questions, and challenges

J Rezaie, M Feghhi, T Etemadi - Cell Communication and Signaling, 2022 - Springer
Background Exosomes are progressively known as significant mediators of cell-to-cell
communication. They convey active biomolecules to target cells and have vital functions in …

Therapeutically harnessing extracellular vesicles

L Cheng, AF Hill - Nature Reviews Drug Discovery, 2022 - nature.com
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

[HTML][HTML] Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?

M Kou, L Huang, J Yang, Z Chiang, S Chen, J Liu… - Cell Death & …, 2022 - nature.com
Mesenchymal stem cells (MSCs) can be widely isolated from various tissues including bone
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …

Extracellular vesicle analysis

A Hendrix, L Lippens, C Pinheiro, C Théry… - Nature Reviews …, 2023 - nature.com
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …

A brief history of nearly EV‐erything–The rise and rise of extracellular vesicles

Y Couch, EI Buzàs, D Di Vizio, YS Gho… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are small cargo‐bearing vesicles released by cells into the
extracellular space. The field of EVs has grown exponentially over the past two decades; this …

Identification of storage conditions stabilizing extracellular vesicles preparations

A Görgens, G Corso, DW Hagey… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological
processes and hold great potential for therapeutic and diagnostic use. Despite significant …

Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles

KW Witwer, DCI Goberdhan, L O'Driscoll… - Journal of …, 2021 - Wiley Online Library
The minimal information for studies of extracellular vesicles (EVs, MISEV) is a field‐
consensus rigour initiative of the International Society for Extracellular Vesicles (ISEV). The …

Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

J Mondal, S Pillarisetti, V Junnuthula, M Saha… - Journal of Controlled …, 2023 - Elsevier
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …