Topical intra-nasal sprays are amongst the most commonly prescribed therapeutic options
for sinonasal diseases in humans. However, inconsistency and ambiguity in instructions …

Background Topical intranasal drugs are widely prescribed for chronic rhinosinusitis (CRS),
although delivery can vary with device type and droplet size. The study objective was to …

The nasopharynx, at the back of the nose, constitutes the dominant initial viral infection
trigger zone along the upper respiratory tract. However, as per the standard recommended …

Background: While the nasopharynx is initially the dominant upper airway infection site for
SARS-CoV-2, the physiologic mechanism launching the infection at the lower airway is still …

Investigations on airborne transmission of pathogens constitute a rapidly expanding field,
primarily focused on understanding the expulsion patterns of respiratory particulates from …

Drug delivery for viral respiratory infections, such as SARS-CoV-2, can be enhanced
significantly by targeting the nasopharynx, which is the dominant initial infection site in the …

This thesis aims to explore efficient drug delivery to clinical target sites along the human
upper airway that strongly depends on variables associated with the delivery device and the …

В данной работе будет рассматриваться численный эксперимент по доставке
препарата в носовые пути. Будет исследовано 2 способа ввода препарата в носовые …

This thesis aims to explore the potential of improving the efficacy of drugs for treatment of
viral infections by targeting the nasopharynx, which is commonly the first site of infection for …

Background: Chronic rhinosinusitis (CRS) is a prevalent and disruptive disease. Medical
management including nasal steroid sprays is the primary treatment modality …