The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology

TE Sandberg, MJ Salazar, LL Weng, BO Palsson… - Metabolic …, 2019 - Elsevier
Harnessing the process of natural selection to obtain and understand new microbial
phenotypes has become increasingly possible due to advances in culturing techniques …

The importance of genomic variation for biodiversity, ecosystems and people

M Stange, RDH Barrett, AP Hendry - Nature Reviews Genetics, 2021 - nature.com
Abstract The 2019 United Nations Global assessment report on biodiversity and ecosystem
services estimated that approximately 1 million species are at risk of extinction. This …

Fungal enzymes for bio-products from sustainable and waste biomass

VK Gupta, CP Kubicek, JG Berrin, DW Wilson… - Trends in biochemical …, 2016 - cell.com
Lignocellulose, the most abundant renewable carbon source on earth, is the logical
candidate to replace fossil carbon as the major biofuel raw material. Nevertheless, the …

Production of fuels and chemicals from xylose by engineered Saccharomyces cerevisiae: a review and perspective

S Kwak, YS Jin - Microbial cell factories, 2017 - Springer
Efficient xylose utilization is one of the most important pre-requisites for developing an
economic microbial conversion process of terrestrial lignocellulosic biomass into biofuels …

Saccharomyces cerevisiae strains for second-generation ethanol production: from academic exploration to industrial implementation

MLA Jansen, JM Bracher, I Papapetridis… - FEMS yeast …, 2017 - academic.oup.com
The recent start-up of several full-scale 'second generation'ethanol plants marks a major
milestone in the development of Saccharomyces cerevisiae strains for fermentation of …

The development and characterization of synthetic minimal yeast promoters

H Redden, HS Alper - Nature communications, 2015 - nature.com
Synthetic promoters, especially minimally sized, are critical for advancing fungal synthetic
biology. Fungal promoters often span hundreds of base pairs, nearly ten times the amount of …

Microbial experimental evolution–a proving ground for evolutionary theory and a tool for discovery

MJ McDonald - EMBO reports, 2019 - embopress.org
Microbial experimental evolution uses controlled laboratory populations to study the
mechanisms of evolution. The molecular analysis of evolved populations enables empirical …

Xylose fermentation efficiency of industrial Saccharomyces cerevisiae yeast with separate or combined xylose reductase/xylitol dehydrogenase and xylose isomerase …

JT Cunha, PO Soares, A Romaní, JM Thevelein… - Biotechnology for …, 2019 - Springer
Background Xylose isomerase (XI) and xylose reductase/xylitol dehydrogenase (XR/XDH)
pathways have been extensively used to confer xylose assimilation capacity to …

Engineering microbes to bio-upcycle polyethylene terephthalate

L Dissanayake, LN Jayakody - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Polyethylene terephthalate (PET) is globally the largest produced aromatic polyester with an
annual production exceeding 50 million metric tons. PET can be mechanically and …

[HTML][HTML] Recent advances in bioethanol production from lignocelluloses: a comprehensive review with a focus on enzyme engineering and designer biocatalysts

Y Lugani, R Rai, AA Prabhu, P Maan… - Biofuel Research …, 2020 - biofueljournal.com
Many countries have their biofuel policy programs in place as part of their overall strategy to
achieve sustainable development. Among biofuels, bioethanol as a promising alternative to …