[HTML][HTML] Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease

YJ Liu, RL McIntyre, GE Janssens… - Mechanisms of ageing …, 2020 - Elsevier
The mitochondria is the major hub to convert energy for cellular processes. Dysregulation of
mitochondrial function is one of the classical hallmarks of aging, and mitochondrial …

Mito-morphosis: mitochondrial fusion, fission, and cristae remodeling as key mediators of cellular function

L Pernas, L Scorrano - Annual review of physiology, 2016 - annualreviews.org
Permanent residency in the eukaryotic cell pressured the prokaryotic mitochondrial ancestor
to strategize for intracellular living. Mitochondria are able to autonomously integrate and …

[HTML][HTML] Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation

A Irazoki, I Gordaliza-Alaguero, E Frank… - Nature …, 2023 - nature.com
Some forms of mitochondrial dysfunction induce sterile inflammation through mitochondrial
DNA recognition by intracellular DNA sensors. However, the involvement of mitochondrial …

[HTML][HTML] Mitofusins, from mitochondria to metabolism

E Schrepfer, L Scorrano - Molecular cell, 2016 - cell.com
Mitochondrial architecture is involved in several functions crucial for cell viability,
proliferation, senescence, and signaling. In particular, mitochondrial dynamics, through the …

Mitochondrial fusion and fission in cell life and death

B Westermann - Nature reviews Molecular cell biology, 2010 - nature.com
Mitochondria are dynamic organelles that constantly fuse and divide. These processes
(collectively termed mitochondrial dynamics) are important for mitochondrial inheritance and …

Mitochondrial membrane potential probes and the proton gradient: a practical usage guide

SW Perry, JP Norman, J Barbieri, EB Brown… - …, 2011 - Taylor & Francis
Fluorescent probes for monitoring mitochondrial membrane potential are frequently used for
assessing mitochondrial function, particularly in the context of cell fate determination in …

Fusion and fission: interlinked processes critical for mitochondrial health

DC Chan - Annual review of genetics, 2012 - annualreviews.org
Mitochondria are dynamic organelles that continually undergo fusion and fission. These
opposing processes work in concert to maintain the shape, size, and number of …

Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity

AM Bertholet, T Delerue, AM Millet, MF Moulis… - Neurobiology of …, 2016 - Elsevier
Mitochondria are dynamic organelles that continually move, fuse and divide. The dynamic
balance of fusion and fission of mitochondria determines their morphology and allows their …

[HTML][HTML] Implications of oxidative stress and potential role of mitochondrial dysfunction in COVID-19: therapeutic effects of vitamin D

N de Las Heras, VM Martín Giménez, L Ferder… - Antioxidants, 2020 - mdpi.com
Due to its high degree of contagiousness and like almost no other virus, SARS-CoV-2 has
put the health of the world population on alert. COVID-19 can provoke an acute inflammatory …

The interplay between mitochondrial dynamics and mitophagy

G Twig, OS Shirihai - Antioxidants & redox signaling, 2011 - liebertpub.com
Mitochondrial dynamics and mitophagy are recognized as two critical processes underlying
mitochondrial homeostasis. Morphological and bioenergetic characterization of the life cycle …