The role of plant‐derived products in pancreatitis: experimental and clinical evidence

P Anchi, A Khurana, S Bale… - Phytotherapy Research, 2017 - Wiley Online Library
Pancreatitis is a gastrointestinal disease with a worldwide sharp surge during the past
decade. Pancreatitis includes acute and chronic subtypes, which are graded based on the …

Dopamine D2 receptor signalling controls inflammation in acute pancreatitis via a PP2A‐dependent Akt/NF‐κB signalling pathway

X Han, B Li, X Ye, T Mulatibieke, J Wu… - British Journal of …, 2017 - Wiley Online Library
Background and Purpose Dopamine has multiple anti‐inflammatory effects, but its role and
molecular mechanism in acute pancreatitis (AP) are unclear. We investigated the role of …

Glycyrrhizin reduces HMGB1 and bacterial load in Pseudomonas aeruginosa keratitis

SA Ekanayaka, SA McClellan… - … & visual science, 2016 - iovs.arvojournals.org
Purpose: High mobility group box 1 (HMGB1) contributes to poor disease outcome in
Pseudomonas aeruginosa keratitis. This study tests the prophylactic effect of treatment with …

Prognostic biomarkers and immunotherapeutic targets among CXC chemokines in pancreatic adenocarcinoma

J Huang, Z Chen, C Ding, S Lin, D Wan, K Ren - Frontiers in oncology, 2021 - frontiersin.org
Background Pancreatic cancer is one of the principal causes of tumor-related death
worldwide. CXC chemokines, a subfamily of functional chemotactic peptides, affect the …

Effects of glycyrrhizin treatment on diabetic cornea

M Somayajulu, SA McClellan… - Journal of Ocular …, 2021 - liebertpub.com
Purpose: To test how glycyrrhizin (GLY) affects mouse corneal epithelial cells (MCEC) and
the diabetic murine cornea. Methods: Viability of MCEC grown under normal or high glucose …

Heme oxygenase-1 induced by desoxo-narchinol-A attenuated the severity of acute pancreatitis via blockade of neutrophil infiltration

GS Bae, DG Kim, IJ Jo, SB Choi, MJ Kim… - International …, 2019 - Elsevier
Abstract Heme oxygenase-1 (HO-1) has an anti-inflammatory action in acute pancreatitis
(AP). However, its mechanism of action and natural compounds/drugs to induce HO-1 in …

Network pharmacology and in vitro experimental verification unveil glycyrrhizin from glycyrrhiza glabra alleviates acute pancreatitis via modulation of MAPK and …

R Zhang, A Asikaer, Q Chen, F Wang, J Lan… - … Medicine and Therapies, 2024 - Springer
Acute pancreatitis (AP) is a severe gastrointestinal inflammatory disease with increasing
mortality and morbidity. Glycyrrhiza glabra, commonly known as Liquorice, is a widely used …

[HTML][HTML] RBPJ Deficiency Sensitizes Pancreatic Acinar Cells to KRAS-Mediated Pancreatic Intraepithelial Neoplasia Initiation

L Pan, MA Mulaw, J Gout, M Guo, H Zarrin… - Cellular and Molecular …, 2023 - Elsevier
Background and Aims Development of pancreatic ductal adenocarcinoma (PDAC) is a
multistep process intensively studied; however, precocious diagnosis and effective therapy …

MiR-204-5p performs a protective effect on cerulein-induced rat pancreatic acinar cell AR42J cell damage by targeting tyrosine 3-monooxygenase/tryptophan 5 …

H Zhao, S Jiang - Pancreas, 2021 - journals.lww.com
Objective This research plans to address the function of miR-204-5p/tyrosine 3-
monooxygenase/tryptophan 5-monooxygenase activation protein gamma (YWHAG) in …

Anti-Inflammatory Effects of Novel Glycyrrhiza Variety Wongam In Vivo and In Vitro

YM Kang, J Lee, W Kim, JS Jin, JH Lee, HJ An - Applied Sciences, 2021 - mdpi.com
Licorice is the common name of Glycyrrhiza species, which is an important plant for edible
and medicinal purposes; however, Glycyrrhiza resources have become limited because of …