Emerging roles of nucleoside transporters
M Pastor-Anglada, S Pérez-Torras - Frontiers in pharmacology, 2018 - frontiersin.org
Since human Nucleoside Transporters (hNTs) were identified by their activity as transport
systems, extensive work has been done to fully characterize them at the molecular and …
systems, extensive work has been done to fully characterize them at the molecular and …
[HTML][HTML] Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread
PP Wong, F Demircioglu, E Ghazaly, W Alrawashdeh… - Cancer cell, 2015 - cell.com
Increasing chemotherapy delivery to tumors, while enhancing drug uptake and reducing
side effects, is a primary goal of cancer research. In mouse and human cancer models in …
side effects, is a primary goal of cancer research. In mouse and human cancer models in …
Intestinal nucleoside transporters: function, expression, and regulation
M Pastor‐Anglada, N Urtasun… - Comprehensive …, 2011 - Wiley Online Library
The gastrointestinal tract is the absorptive organ for nutrients found in foods after digestion.
Nucleosides and, to a lesser extent nucleobases, are the late products of nucleoprotein …
Nucleosides and, to a lesser extent nucleobases, are the late products of nucleoprotein …
Basolateral uptake of nucleosides by Sertoli cells is mediated primarily by equilibrative nucleoside transporter 1
DM Klein, KK Evans, RN Hardwick, WH Dantzler… - … of Pharmacology and …, 2013 - ASPET
The blood-testis barrier (BTB) prevents the entry of many xenobiotic compounds into
seminiferous tubules thereby protecting developing germ cells. Understanding drug …
seminiferous tubules thereby protecting developing germ cells. Understanding drug …
Expression of Concentrative Nucleoside Transporters (SLC28A) in the Human Placenta: Effects of Gestation Age and Prototype Differentiation-Affecting Agents
L Jiraskova, L Cerveny, S Karbanova… - Molecular …, 2018 - ACS Publications
Equilibrative (SLC29A) and concentrative (SLC28A) nucleoside transporters contribute to
proper placental development and mediate uptake of nucleosides/nucleoside-derived …
proper placental development and mediate uptake of nucleosides/nucleoside-derived …
Phosphorylation of RS1 (RSC1A1) steers inhibition of different exocytotic pathways for glucose transporter SGLT1 and nucleoside transporter CNT1, and an RS1 …
M Veyhl-Wichmann, A Friedrich, A Vernaleken… - Molecular …, 2016 - ASPET
Cellular uptake adapts rapidly to physiologic demands by changing transporter abundance
in the plasma membrane. The human gene RSC1A1 codes for a 67-kDa protein named RS1 …
in the plasma membrane. The human gene RSC1A1 codes for a 67-kDa protein named RS1 …
Galectin‐4 interacts with the drug transporter human concentrative nucleoside transporter 3 to regulate its function
P Fernández‐Calotti, O Casulleras… - The FASEB …, 2016 - Wiley Online Library
The intracellular N‐terminal domain of the nucleoside and drug transporter human
concentrative nucleoside transporter (hCNT) 3 was used as bait in a glutathione S …
concentrative nucleoside transporter (hCNT) 3 was used as bait in a glutathione S …
Ischemia/Reperfusion-inducible protein modulates the function of organic cation transporter 1 and multidrug and toxin extrusion 1
The recently identified ischemia/reperfusion-inducible protein (IRIP) has been reported to
negatively modulate the activities of several transporters in cell culture systems. The goal of …
negatively modulate the activities of several transporters in cell culture systems. The goal of …
Protein RS1 (RSC1A1) downregulates the exocytotic pathway of glucose transporter SGLT1 at low intracellular glucose via inhibition of ornithine decarboxylase
C Chintalapati, T Keller, TD Mueller, V Gorboulev… - Molecular …, 2016 - ASPET
Na+-d-glucose cotransporter 1 (SGLT1) is rate-limiting for glucose absorption in the small
intestine. Shortly after intake of glucose-rich food, SGLT1 abundance in the luminal …
intestine. Shortly after intake of glucose-rich food, SGLT1 abundance in the luminal …
THE NUCLEOSIDE TRANSPORTERS CNTs AND ENTs
R Govindarajan, AL Quiñones… - … and Role in Drug …, 2022 - Wiley Online Library
Two gene families, the concentrative nucleoside transporters (CNTs/SLC28) and the
equilibrative nucleoside transporters (ENTs/SLC29), mediate membrane transport of …
equilibrative nucleoside transporters (ENTs/SLC29), mediate membrane transport of …