Obesity and its complications have become a prominent global public health problem that
severely threatens human health. Melatonin, originally known as an effective antioxidant, is …

In type 2 diabetes mellitus (T2DM) and its related disorders like obesity, the abnormal
protein processing, oxidative stress and proinflammatory cytokines will drive the activation of …

Melatonin, a hormone synthesized by both the pineal gland and retina, functions as an
important modulator of a number of physiological functions. In addition to its rather well …

Skeletal muscle disorders are dramatically increasing with human aging with enormous
sanitary costs and impact on the quality of life. Preventive and therapeutic tools to limit onset …

Despite the evolving advances in clinical approaches to obesity and its inherent
comorbidities, the therapeutic challenge persists. Among several pharmacological tools …

Consumption of an exceedingly high-fat diet with irregular eating and sleeping habits is
typical in the current sedentary lifestyle, leading to chronic diseases like obesity and …

Circadian rhythms play a critical role in the physiological processes involved in energy
metabolism and energy balance (EB). A large array of metabolic processes, including the …

Obesity results from critical periods of positive energy balance characterized by caloric
intake greater than energy expenditure. This disbalance promotes adipose tissue …

The circadian clock is a biological timekeeping system to govern temporal rhythms of the
endocrine system and metabolism. The master pacemaker of biological rhythms is housed …

The use of the sleep‐promoting hormone melatonin is rapidly increasing as an assumed
safe sleep aid. During the last decade, accumulating observations suggest that melatonin …