Ginsenoside Rg1 in neurological diseases: From bench to bedside

S Yang, J Wang, P Cheng, L Chen, J Hu… - Acta Pharmacologica …, 2023 - nature.com
Ginseng has been used in China as a superior medicinal material for thousands of years
that can nourish the five internal organs, calm the mind and benefit wisdom. Due to its anti …

Neuroprotective effects of ginseng phytochemicals: recent perspectives

X Huang, N Li, Y Pu, T Zhang, B Wang - Molecules, 2019 - mdpi.com
As our global population ages, the treatment of neurodegenerative diseases is critical to our
society. In recent years, researchers have begun to study the role of biologically active …

Mechanisms of Panax ginseng action as an antidepressant

Y Jin, R Cui, L Zhao, J Fan, B Li - Cell proliferation, 2019 - Wiley Online Library
Objectives Panax ginseng, a well‐known traditional Chinese medicine with multiple
pharmacological activities, plays a crucial role in modulating mood disorders. Several recent …

Panax notoginseng saponins: a review of its mechanisms of antidepressant or anxiolytic effects and network analysis on phytochemistry and pharmacology

W Xie, X Meng, Y Zhai, P Zhou, T Ye, Z Wang, G Sun… - Molecules, 2018 - mdpi.com
Panax notoginseng (Burk) FH Chen, as traditional Chinese medicine, has a long history of
high clinical value, such as anti-inflammatory, anti-oxidation, inhibition of platelet …

Ginsenoside Rg1 prevent and treat inflammatory diseases: A review

Y Gao, J Li, J Wang, X Li, J Li, S Chu, L Li… - International …, 2020 - Elsevier
Ginseng has been used as reinforcing drugs or for traditional Chinese medicine in aging,
inflammation, stress, diabetes mellitus, hepatic diseases and cancer. The aim of this current …

[HTML][HTML] The neuroprotective effect of traditional Chinese medicinal plants—A critical review

J Moreira, M Machado, M Dias-Teixeira… - … Pharmaceutica Sinica B, 2023 - Elsevier
Neurodegenerative and neuropsychiatric diseases are increasingly affecting individuals'
quality of life, thus increasing their cost to social and health systems. These diseases have …

Ginsenoside-Rg1 synergized with voluntary running exercise protects against glial activation and dysregulation of neuronal plasticity in depression

W Wang, L Wang, L Wang, Y Li, T Lan, C Wang… - Food & function, 2023 - pubs.rsc.org
Depression is a common psychological disease accompanied by mental disorders and
somatic symptoms. However, the underlying mechanisms regarding the pathogenesis of …

Ginsenoside Rg1 ameliorates chronic social defeat stress-induced depressive-like behaviors and hippocampal neuroinflammation

N Jiang, J Lv, H Wang, H Huang, Q Wang, C Lu… - Life sciences, 2020 - Elsevier
Chronic social defeat stress (CSDS) is an ethologically relevant psychosocial stress animal
model and has been widely used in depression studies. Ginsenoside Rg1 (Rg1) is the major …

[HTML][HTML] Effect of salidroside on neuroprotection and psychiatric sequelae during the COVID-19 pandemic: a review

T Zhu, H Liu, S Gao, N Jiang, S Chen, W Xie - Biomedicine & …, 2024 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has affected the mental
health of individuals worldwide, and the risk of psychiatric sequelae and consequent mental …

Ginsenosides in central nervous system diseases: Pharmacological actions, mechanisms, and therapeutics

J Lu, X Wang, A Wu, Y Cao, X Dai… - Phytotherapy …, 2022 - Wiley Online Library
The nervous system is one of the most complex physiological systems, and central nervous
system diseases (CNSDs) are serious diseases that affect human health. Ginseng (Panax …