Ionic liquids1 are substances that are completely composed of ions and are liquid at or close
to room temperature. Interest in these compounds, often heralded as the green, high-tech …

Biotransformations already represent an effective and sometimes preferable alternative to
chemical synthesis for the production of fine chemicals and optically active compounds. To …

The Handbook of Pharmaceutical Controlled Release Technology reviews the design,
fabrication, methodology, administration, and classifications of various drug delivery …

Although numerous protein therapeutics have been approved or are in advanced clinical
testing, the development of more sophisticated delivery systems for this rapidly expanding …

The fabrication of hydrogel microstructures based upon poly (ethylene glycol) diacrylates,
dimethacrylates, and tetraacrylates patterned photolithographically on silicon or glass …

Freeze-Drying/Lyophilization Of Pharmaceutical & Biological Products, Revised and Expanded
Page 1 DRUGS AND THE PHARMACEUTICAL SCIENCES Executive Editor James Swarbrick …

Recent work has largely completed our understanding of the hydrogen-exchange chemistry
of unstructured proteins and nucleic acids. Some of the high-energy structural fluctuations …

Changes in the secondary structure of some dozen different proteins upon lyophilization of
their aqueous solutions have been investigated by means of Fourier-transform infrared …

Objectives Enzyme/metal-organic framework composites with high stability in protein
denaturing solvents were reported in this study. Results Encapsulation of enzyme in metal …

Enzymatic reactions in nonaqueous solvents offer new possibilities for the biotechnological
production of many useful chemicals using reactions that are not feasible in aqueous media …