As medical and pharmacological technology advances, new and complex modalities of
disease treatment that are more personalized and targeted are being developed. Often …

Abstract Di-2-ethylhexyl phthalate (DEHP) has been widely used in many fields (agricultural
products, medical instruments, and food packing). As an environmental contaminant, DEHP …

Lipid droplets are the essential organelle for storing lipids in a cell. Within the variety of the
human body, different cells store, utilize and release lipids in different ways, depending on …

Di (2-ethylhexyl) phthalate (DEHP) is a widespread pollutant that badly affects animals and
human health. Lycopene (LYC) has been used as a dietary supplement that has effective …

Liver-generated plasma apolipoprotein E (apoE) does not enter the brain but nonetheless
correlates with Alzheimer's disease (AD) risk and AD biomarker levels. Carriers of APOE ε4 …

The synchronization of circadian clock depends on a central pacemaker located in the
suprachiasmatic nuclei. However, the potential feedback of peripheral signals on the central …

Chronic liver disease is a major public health problem with a high and increasing
prevalence worldwide. In the progression of chronic liver disease, steatosis drives the …

The microenvironment of distant organ plays vital roles in regulating tumor metastases.
However, little is known about the crosstalk between metastasized tumor cells and target …

Nuclear receptors (NRs), a superfamily of ligand-activated transcription factors, are critical in
cell growth, proliferation, differentiation, metabolism, and numerous biologic events. NRs …

Peroxisome proliferator‐activated receptor alpha (PPARα, NR1C1) belongs to a large family
of ligand‐dependent nuclear receptors (NRs). It is one of the best studied NRs which …