Toll‐like receptors (TLRs): structure, functions, signaling, and role of their polymorphisms in colorectal cancer susceptibility

AS Sameer, S Nissar - BioMed Research International, 2021 - Wiley Online Library
Toll‐like receptors (TLRs) are the important mediators of inflammatory pathways in the gut
which play a major role in mediating the immune responses towards a wide variety of …

[HTML][HTML] The role of Toll-like receptors and neuroinflammation in Parkinson's disease

A Heidari, N Yazdanpanah, N Rezaei - Journal of Neuroinflammation, 2022 - Springer
Background Parkinson's disease (PD) is the second most prevalent neurodegenerative
disorder, characterized by motor and non-motor symptoms, significantly affecting patients' …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

Toll-like receptor 4 (TLR4) inhibitors: Current research and prospective

Y Zhang, X Liang, X Bao, W Xiao, G Chen - European journal of medicinal …, 2022 - Elsevier
Abstract Toll-like receptor 4 (TLR4), a member of the Toll-like receptor (TLR) family, is
involved in innate immunity and mediates inflammatory responses by recognizing …

[HTML][HTML] The roles of autophagy in cancer

CW Yun, SH Lee - International journal of molecular sciences, 2018 - mdpi.com
Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …

[HTML][HTML] Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities

MA Ortega, MA Álvarez-Mon, C García-Montero… - Molecular …, 2023 - nature.com
Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

Cell death signaling

DR Green, F Llambi - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
In multicellular organisms, cell death is a critical and active process that maintains tissue
homeostasis and eliminates potentially harmful cells. There are three major types of …

Cell signaling and stress responses

GS Hotamisligil, RJ Davis - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Stress-signaling pathways are evolutionarily conserved and play an important role in the
maintenance of homeostasis. These pathways are also critical for adaptation to new cellular …

The noncoding and coding transcriptional landscape of the peripheral immune response in patients with COVID‐19

H Tang, Y Gao, Z Li, Y Miao, Z Huang… - Clinical and …, 2020 - Wiley Online Library
Background COVID‐19 is currently a global pandemic, but the response of human immune
system to severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection …

[HTML][HTML] Toll-like receptors and inflammatory bowel disease

Y Lu, X Li, S Liu, Y Zhang, D Zhang - Frontiers in immunology, 2018 - frontiersin.org
Inflammatory bowel disease (IBD) is one relapsing and lifelong disease that affects millions
of patients worldwide. Increasing evidence has recently highlighted immune-system …